Job description
Site Name: USA - Pennsylvania - Upper Providence, Switzerland - Zug, UK - London, USA - Massachusetts - Waltham, Warsaw
Posted Date: Nov 26 2025

GSK Oncology Early Clinical Development is seeking a highly skilled and motivated Early Clinical Development Medical Director- Oncology, to join our dynamic Oncology Research and Development team. In this role the successful candidate will create a strong link between Clinical Development and Pre-clinical/ Discovery teams to improve forward and reverse translation and, thereby, increase the success of our Oncology clinical portfolio in the prostate cancer space. This role offers a unique opportunity to bridge the gap between preclinical research and clinical development, ensuring the successful translation of innovative therapies from the lab to the clinic.

The Early Clinical Development Medical Director- Oncology will report to the Executive Medical Director, Early Clinical Development Lead (ECDL)-GU, Oncology Clinical Development.� The Medical Director will be responsible for clinical research activities pertaining to advancing the development of GSK�s clinical portfolio and will also have responsibility for engaging in medical dialogues with relevant scientific and medical leaders in order to lead clinical data generation activities. This individual will also have a leading role in managing effective relationships with Key External Experts.

This role requires a physician capable of developing and executing oncology clinical trials, in support of the successful clinical development, regulatory filing and initial market launch of a growing portfolio of innovative and transformational Oncology agents for patients with prostate cancer.

Please note: This position requires an on-site office -based presence 2 to 3 days a week in the UK (London or Stevenage); Switzerland (Zug); US (Upper Providence, PA. Waltham. MA or Boston. MA); or Poland (Warsaw).

Key responsibilities

• Collaborate with physicians, scientists, regulatory professionals, biostatisticians, regulatory, executive staff and others in a complex matrix environment to develop and execute early phase interventional clinical trials for patients with prostate cancer.
• Ensure high quality protocol development aligned with the overall Clinical Development Plan for assets to effectively determine a medicine�s potential efficacy, safety profile, key areas of product differentiation and value to patient in the shortest possible timeframe.�
• Use medical expertise to contribute to the end to end (protocol concept to final study report) to ensure scientific integrity and timely delivery of clinical trials which ensure consistency with the clinical development strategy for regulatory approvals, reimbursable medicines, and successful lifecycle management; demonstrate ability to incorporate global considerations into decision making�
• Interpret and summarize study results consistent with objectives to define safety, efficacy, pharmacokinetic/pharmacodynamic, and patient reported outcomes, and applicability of data to the targeted prostate cancer patient population.��
• Assume medical responsibility for clinical trials with active participation in real-time medical monitoring of studies, including patient eligibility assessment, study design questions, and addressing urgent safety questions (with inclusion of Safety/ PV as relevant).
• Assume responsibility for medical review of clinical trial data, both directly as needed and/or via oversight of delegated medical review. Oversee review of data packages intended for internal and/or external IDMCs.
• Review/monitor safety data in collaboration with pharmacovigilance group for active clinical studies.
• Participate in the authoring of clinical study reports and regulatory documents and collaborate with colleagues in Regulatory Affairs, CMC, Toxicology, Research, Pharmacology to respond to health authority and ethics committee queries.
• Collaborate with Principal Investigators in the evaluation and assessment of data during dose escalation and expansion studies and subsequent publications (abstracts, posters, manuscripts) associated with clinical data.
• Network extensively to develop long-term strategic partnerships with thought leaders both internally and externally, in support of GSK�s vision.
• Understand biological mechanisms, clinical strategy, scientific interpretation of disease and target-based literature.�
• Serve as a core member of the Clinical Matrix Team for one or more assets in development.
• Represent Clinical Development on disease area strategy, integrated evidence and medical affairs strategy teams.
• Participate in Oncology Clinical Development-wide initiatives and workstreams as appropriate.

Why You?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• Medical degree from accredited medical school?�

• Completion of a clinical residency program�

• Experience in clinical research and development�in Oncology

• Experience working in the pharmaceutical/biotechnology industry in prostate cancer.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Oncology experience in pharmaceutical/biotechnology industry preferred

• Experience in leading oncology clinical trials, including experience with study design, data review/interpretation and the overall clinical development process

• Robust knowledge of disease-specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution�

• Experience in regulatory requirements to support registration, including knowledge and adherence to GCP principles

Why GSK?

Our values and expectations�are at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

• Agile and distributed decision-making � using evidence and applying judgement to balance pace, rigour and risk
• Managing individual and team performance.
• Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
• Implementing change initiatives and leading change.
• Sustaining energy and well-being, building resilience in teams.
• Continuously looking for opportunities to learn, build skills and share learning both internally and externally.
• Developing people and building a talent pipeline.
• Translating strategy into action - a compelling narrative, motivating others, setting objectives and delegation.
• Building strong relationships and collaboration, managing trusted stakeholder relationships internally and externally.
• Budgeting and forecasting, commercial and financial acumen.

� If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $176,250 to $293,750. The US salary ranges take into account a number of factors including work location within the US market, the candidate�s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit� GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job description
Site Name: UK � London � New Oxford Street
Posted Date: Nov 10 2025

This is an individual contributor position in the HIV Therapeutic Area and will serve as Safety Lead for a product.

Responsible to lead medical and scientific staff within the SERM (Safety Evaluation & Risk Management) group and defining and driving the strategy and vision of clinical safety and pharmacovigilance activities in alignment with Global Safety business strategies.

�As a senior member of the Global Safety organization the role is responsible to:�

• Implement policy, processes and support the implementation of operational and strategic plans�
• Ensure scientifically sound review and interpretation of data and management of safety issues and escalates safety issues identified through the safety review process to senior management and safety governance as appropriate. Makes recommendations for the further characterization, management, and communication of safety risks�
• Focus on efficiency and effectiveness to meet the needs of our Patients and HCPs.� Supporting the pharmacovigilance and benefit-risk management of the assigned portfolio of GSK global assets to ensure Patient Safety globally.��

Key Responsibilities

Scientific/Medical Knowledge PV Expertise

• Expert in clinical safety and pharmacovigilance activities.
• Demonstrated record of sound judgement and decision making in safety evidence generation, benefit-risk assessment, causality assessment, evaluation of safety signals, and of proactive risk management strategies including management of labelling changes, physician and patient education and monitoring of safety issues in the real world.
• Coaches and mentors SERM colleagues in the scientific/medical aspects of signal evaluation methodology and risk management and preparation of regulatory safety reports and other documents.
• Demonstrated track record of quality decision making and creative problem resolution in critical situations, based on assessment of all relevant supporting and conflicting information/factors and understanding of the wider context.
• Provides excellent medical/scientific judgment, strong analytical skills, proactive approach in drug safety and high sense of urgency.
• Champions/sponsors safety governance by development of safety strategy and its execution for products in clinical development and post marketing settings. Anticipates, detects and addresses product safety issues and ensures that risk-reduction strategies are implemented appropriately.
• Leads cross-GSK activities such as safety advisory panels, interfaces with and assumes ad hoc membership of a Senior Governance Committee.
• Ability to engage in, and contribute to, broad GSK environment and pharmacovigilance environment outside GSK with confidence, impact, integrity and professionalism.

Cross-functional Matrix team leadership

• Proven ability to affect department, or product strategies with a strong understanding and ability to incorporate global considerations into decision making.
• Builds strong collaborative relationships and displays excellent leadership skills on safety issues whilst working in a matrix team, with an outstanding track record leading a team in a matrix setting.
• Demonstrates resilience and ability to adjust behaviours and priorities based on changing environment.
• Leads or oversees SERM contribution to due diligence activities.

Communications (verbal, written) and Influencing (internal PV Governance and External LTs)

• Excellent communication (verbal, written) and influencing (internally and externally) skills.
• Leads cross-GSK activities such as safety advisory panels, interfaces and assumes ad hoc membership of a Senior Governance Committee. Influences others external to GSK to meet organisational objectives and may be recognised as a key player in external international pharmacovigilance activities (i.e., may be a member of trade association or external initiatives).
• Leads driving change until their implementation.
• Recognised as an authority with expert knowledge of relevant pharmacovigilance regulations and methodologies applicable to SERM activities.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• Medical degree for Senior Medical Director or Health Sciences/Health Care Professional degree (e.g., BSc, MS, PhD, RN/BSN/MSN, NP, RPh/B Pharm/Pharm D) for Senior Scientific Director�
• Comprehensive experience in the Pharmaceutical or Biotech industry working in Pharmacovigilance or Drug Safety
• Significant pharmacovigilance experience relating to Safety Evaluation and Risk Management, encompassing both clinical development and post-marketing activities
• Knowledge/experience of international pharmacovigilance requirements (e.g., ICH, GVP modules, CIOMS initiatives) and drug development and approval processes.
• Experience working in large matrix organizations.
• Prior experience in the HIV therapy area is desirable but not essential

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391.� The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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Job description
Site Name: UK � London � New Oxford Street, USA - Pennsylvania - Upper Providence
Posted Date: Dec 3 2025

Supported Studies Director

Locations � GSK HQ, New Oxford Street & USA - Upper Providence

Reports to: Head of Interventional & Supported Studies

The key purpose of the Supported Studies Director is to lead the team to deliver studies across all TA.

The Supported Studies Delivery leads and oversees the strategic planning, innovation, execution and management of all supported studies (IIS and SCS) within GSK, including Chief Patient Officer (CPO) Organization, Global Health, Vaccines and R&D

In this role you are the supported studies global process owner (GPO). As the GPO, you are responsible for the end-to-end supported studies process and systems to ensure all supported studies are conducted to the highest standards of quality, ethics, and efficiency, utilizing the latest innovations, systems and best in class practices.

In this role, you will:

• Lead the Supported Study ��TA Teams to execute supported studies with high quality to schedule and budget.
• Manage the Supported �TA Leads to optimize TA level study timelines and scenarios to facilitate delivery of supported studies portfolio in line with Areas of Interest.�
• Ensure feasibility of proposals and provide appropriate oversight of proposals deemed of interest to ensure a high-quality, cost-efficient way to meet timelines
• Review proposals across all TA to ensure operational feasibility and consistency within program.
• Accountable for ensuring successful end to end operational support for the lifecycle of all studies ��across all TA.
• Plan, allocate, review and organize staff assignments. Provide leadership, coaching, guidance as well as training and staff development opportunities. Responsible for hiring and performance management process.
• Drive innovative approaches to study delivery through external facing advances in technology and sciences.
• Review budget forecasts for future studies and ensure they are accurately represented in in the financial system.
• Collaborate across TA's; General Medicine, Global Health, Specialty, Oncology, Vaccines to identify process inefficiencies and lead solution development and implementation.

Basic Qualifications & Skills

• Bachelor�s degree in a relevant field (e.g., Life Sciences, Medicine, Pharmacy, or related area).
• Significant proven experience in clinical study delivery and execution gained from a pharmaceutical organization.
• Previous experience managing cross-functional teams in a global setting.
• Demonstrated leadership experience in managing people, including hiring, performance management, and staff development.
• Strong organizational skills with the ability to manage and prioritize multiple complex studies.
• Excellent communication and interpersonal skills to collaborate across teams and escalate issues effectively.
• Experience working with senior stakeholders such as TA Heads, Medical Affairs Leads, and Portfolio Managers.
• Expertise in driving innovation in study delivery, including leveraging advanced technologies and scientific approaches.

Preferred Qualifications & Skills

• MSc, PhD or MBA in a relevant field with significant experience leading complex, high-priority clinical studies or programs.
• Strategic thinking and decision-making abilities to optimize study timelines and portfolio delivery.
• Advanced problem-solving skills to address operational challenges and risks effectively.
• Ability to collaborate across therapeutic areas to identify inefficiencies and implement solutions.
• Deep understanding of therapeutic areas relevant to GSK portfolio (e.g., General Medicine, Global Health, Specialty, Oncology, Vaccines).
• Familiarity with global clinical operations frameworks, including budget management systems and forecasting tools.
• Familiarity with clinical trial processes, timelines, and regulatory requirements.
• Understanding of therapeutic areas and related Areas of Interest (e.g., General Medicine, Oncology, Vaccines).

We are committed to creating an inclusive workplace where everyone can thrive. If you are passionate about making a difference and have the skills and experience, we are looking for, we encourage you to apply.

Closing Date for Applications: 4th January 2026 (EOD)

Please take a copy of the Job Description, as this will not be available post closure of the advert.?When applying for this role, please use the �cover letter� of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391.� The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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Job description
Site Name: UK - Hampshire, UK - Berkshire, UK - Oxfordshire
Posted Date: Dec 3 2025

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK

Key Account Manager, South Central

GSK is seeking a dynamic and results-oriented Key Account Manager (KAM) to join our team to launch a new Respiratory asset that significantly impacts patients' quality of life and poses a substantial burden on healthcare systems. This role is critical in driving the uptake of GSK products, building strategic partnerships, and improving patient access to innovative therapies that address unmet needs in respiratory disease management.

In this role you will

• Drive product uptake by influencing prescribing decisions and establishing GSK therapies as preferred options for respiratory patients.

• Develop and execute strategic account plans, collaborating with cross-functional teams to achieve objectives.

• Build strong relationships and partnerships with NHS stakeholders, fostering collaboration and trust.

• Communicate clinical data effectively, highlighting the benefits and NHS advantages of GSK therapies for respiratory management.

• Enhance patient access by mapping service pathways, identifying and overcoming barriers, and supporting local access to treatments.

• Monitor progress and adapt strategies using KPIs, data-driven insights, and an understanding of commissioning and reimbursement decisions.

Why you?

Basic Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

• Proven experience in healthcare or pharmaceutical account management or sales.

• Proven experience in product launches, including planning, execution, and monitoring of launch success metrics.

• Current ABPI certification.

• NHS knowledge and experience of working in a specialised disease area (specialised respiratory and/or biologics) or relevant alternative therapeutic areas.

• Proven ability to work across boundaries with highly specialised external experts, relevant payors, and internal stakeholders.

• Ability to present complex concepts clearly. Skilled in interpersonal interaction, communication, and influence, both within the organization and externally.

When applying, please ensure you specify the territories you are familiar with and have experience working in, as we are hiring across multiple locations in the UK

#LI-GSK #LI-remote

Please take a copy of the Job Description, as this will not be available post closure of the advert.�

When applying for this role, please use the �cover letter� of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people�s lives.?GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients� needs and have the highest probability of success. We�re uniting science, technology, and talent to get ahead of disease together.

Find out more: �

Our approach to R&D.???

This is a remarkable chance to be part of a newly formed specialist team, playing a pivotal role in helping GSK achieve its vision of bringing innovative medicines to patients in the UK.

We�re excited about the future and look forward to hearing from you.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391.� The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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Job description
Site Name: USA - Pennsylvania - Upper Providence, Belgium-Wavre, GSK HQ, USA - North Carolina - Durham
Posted Date: Oct 1 2025

The Director, Medical Information & Content Approval, Vaccines plays a critical role in managing a team that ensures the US and global promotional and non-promotional content meets the highest standards of quality, scientific accuracy, balance, and compliance that meets the scientific needs of customers to help inform clinical care and formulary access decisions. This includes ensuring the adherence to internal GSK standards and applicable external regulations, including an understanding of the ABPI code of practice. �This role supports the Sr. MI &CA Director to develop and execute the Medical Information and Content Approval strategy, including innovative digital MI solutions. The Director serves as an influential partner to Medical Affairs, Commercial and other key business stakeholders.

Key Responsibilities:

Leadership:

• Lead and oversee the Global Medical Information and Content Approval? Team for the Vaccines therapeutic area (TA), who are sought out as subject matter experts for their products within the broader medical organization.

• Contribute to the development and execution of the Global Medical Information and Content Approval strategic priorities, including digital solutions, to ensure internal/external stakeholder information needs are optimally met.

• Leading and managing team members to ensure performance objectives are met, providing mentorship and coaching team to support development and resolve challenges.

• Mentor and develop team members, ensuring they have adequate training and tools, and facilitate their professional development through differentiated development plans.

• Act as a delegate of the Senior Director, Medical Information and Content Approval at Leadership team meetings and other relevant meetings requiring TA specific leadership attendance, as required.

MI and Content Approval:

• Accountable for MI launch readiness plans including planning and maintaining a robust, high quality and up to date MI database incorporating medical insights to help inform clinical decision making by HCPs

• Maintain a robust understanding of, and stay up to date with changes to, the ABPI Code of Practice and other regulatory guidelines to assist team members and escalate, when appropriate.

• Ensures team members complete thorough and timely review of promotional and non-promotional US and global materials, ensuring content is scientifically accurate, meets the scientific rigor (i.e., levels of evidence); is fair-balanced and meets the compliance requirements/standards.�

• Accountable for ensuring MI requirements of the payer strategy for the U.S are met.

• Partner with GMI Contact Centre (MI CC) Director/s to ensure the MI CC staff are well trained on new products or new scientific data in a timely manner.

• Work alongside various business partners and leaders (e.g., Legal, Medical, Clinical, Regulatory, Commercial) to align, validate, and identify solutions to ensure content is of the highest quality and relevant to the audience.

• Support GMI&CA team activities (e.g. MI content creation, medical review and approval), when required and in onboarding new team members.

Cross-functional Collaboration:

• Strategically partner with key global TA and US medical stakeholders to maintain a good understanding of the medical strategy of high-priority assets of the TA and ensure MI meets the needs of HCPs worldwide.�

• Ensure effective scientific exchange with external customers, driving excellence in MI activities at important US and Global Congresses, leveraging innovative digital solutions.

• Represent Medical Information and Content Approval on cross functional or medical leadership meetings/forums of the TA area of responsibility.

• Work alongside various business partners and leaders (e.g., Legal, Medical, Clinical, Regulatory, Commercial) to align, validate, and identify solutions to ensure content is of the highest quality and relevant to the audience.

Why You?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• PharmD, MD, PhD, or equivalent.

• 6+ years of experience in the pharmaceutical industry.

• 4+ years of experience in medical writing and/or promotional review and approval.

• 4+ years of experience in customer-focused, problem-solving, and conflict resolution roles.

• Experience in people leadership, management and development

• Experience working in a highly dynamic, changing, and matrixed environment.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Experience communicating and translating evidence and customer insights to/with matrix team partners; proven ability to develop innovative, customer-focused medical solutions and resources

• Experience of working at both global and local country level

• Experience in Vaccines

• Experience influencing internal and external stakeholders on priorities and needs to fill scientific data gaps or needs of external customers

• Strong understanding of international Codes of Practice FDA, IFPMA, EFIPIA, IPHA, ABPI, etc.

• Experience in reviewing and approving promotional and non-promotional content

• Ability to develop and maintain strong trusted relationships with internal stakeholders.

• Demonstrated customer-focus, problem-solving abilities, and strong conflict resolution skills.

• Strong clinical literature evaluation skills

• Strong communication skills

Please visit� GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job description
Site Name: UK - Hertfordshire - Stevenage, UK � London � New Oxford Street, USA - Massachusetts - Boston, USA - Pennsylvania - Upper Providence
Posted Date: Sep 8 2025

The Clinical Development Director - Hepatology provides clinical and scientific insights and leadership to clinical and translational studies or programs within the Early Pipeline Unit (EPU) of the Respiratory, Immunology and Inflammation Research Unit (RIIRU). The appointed individual will work within project teams to plan, execute, and deliver activities including hepatology translational and clinical development strategies and clinical studies, particularly within the area of steatotic liver disease (SLD). You will work cross-functionally to develop and execute clinical development plan(s) up to, and including, Proof of mechanism/Proof of concept studies.

This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following:

Key Accountabilities / Responsibilities:

• Support alignment of translational and clinical plans and study designs with project strategies to ensure quality execution of IEP and CDP. Will develop sections of core regulatory documents.
• Generate the data and evidence required to determine a target or medicines� potential efficacy, safety profile, key areas of product differentiation and route to becoming a medicine with value to patients in the shortest possible timeframe
• Define and deliver the clinical pillars of the translational table. Deliver clinical development and study timelines and endpoints, including pharmacology, mechanism and clinical efficacy endpoints, enabling key decision points and Go/No Go criteria for the CDP.
• Seek and maintain relationships with program counterparts in Biology, Translational, Commercial, Research, Regulatory, Clinical Operations, Access, Medical Affairs and Statistics.
• Contribute to the implementation and embedding of strategic initiatives and various organizational initiatives in Clinical Development

Clinical Development Strategy; Study & Program Design:

• Provides effective support and oversight of R&D evidence generation activities to assure patient safety and study delivery.
• Contributes to the study team discussions on indication planning, incorporates input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc) to contribute to vital deliverables including early Medicine Profile, Target Validation, Translational Plans, Candidate Selection.
• Designs clinical development plans and study protocols across all phases of development, reflecting internal and external stakeholder input (e.g. patients, evidence generation, regulators, payors, pharmacovigilance)
• Develops clinical study protocols, amendments, investigator brochures, clinical study reports etc.
• Inputs to regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.
• Provides medical monitoring and oversight of the safety of study participants on behalf of the Sponsor during the study, together with Pharmacovigilance Physician. If physician, accountability for Medical Governance across the project to ensure scientific integrity and overall safety of the study subjects across the study.

Clinical Leadership:

• Accountable for leading the CMT on an EPU program.� Serves as a clinical point of contact both internally and externally for an indication of an asset indication (i.e. Pre-POC and single indication) or for a clinical study. Represents the clinical matrix team at EDT or clinical study at CMT.
• Collaborate with cross-functional teams, including biology, translational, regulatory affairs, medical affairs, and commercial teams, to ensure cohesive and comprehensive translational and clinical development plans. Act as Clinical Lead at study level.
• Actively leads the end-to-end clinical development strategy for an EPU program and may contribute to later stages.� Serve as the primary point of contact for an investigational agent (early development) or clinical study for internal and external stakeholders, including regulatory agencies, key opinion leaders, and clinical investigators.
• Serves as the primary clinical interface with the relevant internal RIIRU/GSK review board (ie Technical Review or governance) and/or Protocol Review Board.
• Clinical evaluation of business development opportunities.
• Stays abreast of advancements in hepatology research, clinical trial methodologies, competitive environment and regulatory space to maintain GSK�s competitive edge. Identifies and highlights transformational opportunity where projects can offer highly significant benefit to patients in ways not possible with existing approaches.
• Gathers and supports the integration of inputs from across disciplines (scientific, clinical commercial, regulatory) to contribute to clinical components of the Medicine Profile. Consistently contributes to solving study and overall clinical development plan problems.
• Contributes to the implementation and embedding of strategic initiatives and various organizational initiatives in the EPU.
• Demonstrates ability to influence others at project, departmental and inter-departmental levels, as appropriate

Influencing and inspiring others, managing conflict:

• Able to consistently inspire others by setting a positive example, communicating a compelling vision, and creating an environment where team members feel valued and motivated.
• Demonstrated experience in managing conflicts effectively and independently, negotiating mutually acceptable solutions.
• Consistently achieves desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support.

Enterprise mindset and navigating ambiguity:

• Demonstrated flexibility and adaptability in changing environments, able to analyze incomplete information, identify potential risks and implications, and make informed decisions.
• Demonstrated enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.
• Embraces challenge as an opportunity for creativity and uses new learning and digital tools to create innovation in other areas
• Proactively generates ideas for innovative improvement and takes advantage of opportunities that arise; promotes environment for others to generate ideas for improvement

�

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• PhD or PharmD (or equivalent) with 1-3 years postgrad experience in a relevant postgraduate training or job.
• Minimum of 3 years of experience in clinical research and development (may include postgrad experience)
• Knowledge of and experience in the execution of translational studies including both generation and analysis of human translational data and conduct of preclinical biological experiments in relevant model systems
• Robust knowledge of hepatology specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution.
• Experience working with global regulatory agencies and managing global clinical trials in hepatology.
• Knowledge of regulatory requirements, Good Clinical Practice (GCP), and ethical guidelines for clinical research.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Medical Degree Preferred
• Board certified/eligible in hepatology
• General internal medicine preferred for MDs or alternative experience in the relevant disease area

Why GSK?

Our values and expectations�are at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391.� The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

����

Job description

Are you a leading expert in COPD, driven by a passion for transforming clinical insights into groundbreaking therapies and advancing early drug development? If so, the Senior Medical Director � Respiratory Translational Medicine role within GSK�s Early Portfolio Unit offers an exciting opportunity to shape the future of COPD treatment and strategy.

GSK are seeking a Senior Medical Director � Respiratory Translational Medicine with deep expertise in chronic obstructive pulmonary disease (COPD) to join GSK�s Early Portfolio Unit (EPU). The ideal candidate will have a strong background in translational research and demonstrated expertise in bridging clinical insights and experimental medicine to accelerate the development of novel therapies. In joining the Early Portfolio Unit, they will bring extensive clinical expertise and scientific experiences to advancing molecule to first-in-human studies through to early proof-of concept studies, ensuring innovative approaches in COPD and related indications are effectively translated into patient benefit. As a disease expert for COPD, the candidate will have a critical role in co-leading the COPD Disease Area Acceleration Team, a key strategic role supporting and driving our strategy for COPD and must be adept at leading and driving the performance of large matrix teams.

About RIIRU:

The Respiratory, Immunology and Inflammation Research Unit (RIIRU) was formed in 2024 to identify and advance novel molecular targets with genetic associations to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two-fold. The remit of RIIRU is to identify novel targets based on human genetics, develop assets for clinical studies, and perform up to Phase 2 studies in clinic. This goal is enabled through strategic external (e.g., Flagship Pioneering, Vesalius, Muna Therapeutics and others) and GSK-internal partnerships (Research Technologies).??

�in conversation with Tonya Winders, President and CEO of the Global Allergy and Airways Patient Platform, and Dr. Jean Wright, CEO of the COPD foundation

Go�Behind the Science�with our new article featuring Dr Kaivan Khavandi, as he talks about the importance of our respiratory innovation for COPD patients

Read more from Tony Wood�as he explains the importance of prevention in respiratory care

Read our curtain raiser press release�summarizing our key data

PLEASE NOTE: This career opportunity requires an on-site office presence (minimum of two days a week) in one of GSK�s US�(PA or MA) or UK (London - New Oxford Street or Stevenage) sites.

Key Responsibilities:

Scientific Leadership:

• Provide disease-level leadership, to develop causal maps of relevant pathobiology (through identifying, accessing or generating translational datasets), and the tools/instruments (endpoints, biomarkers) that enable timely experimentation and prosecution to derisk mechanisms and programmes.
• Provide translational and clinical leadership in defining and executing innovative early translational and clinical development strategies for COPD programmes in the Early Pipeline Unit. Provide strategic leadership assuring that the clinical study designs are aligned with the IEP and CDP, incorporating the scientific rationale, regulatory requirements, product development plan and commercial goals.
• Stay abreast of advancements in respiratory research, with a focus on COPD and related airways disease, clinical trial methodologies, and regulatory changes to maintain GSK�s competitive edge.
• Actively contribute to regulatory interactions, including briefing documents, presentations, and responses.
• Contribute to Business Development activities, including due diligence projects.
• Champion the implementation of translational and biomarker strategies across the early respiratory portfolio.

DAAT Leadership:

• Co-lead the COPD Disease Area Acceleration Team (DAAT), ensuring alignment of scientific and clinical strategies with business objectives through matrix leadership of large cross-functional teams.
• Drive the evaluation of therapeutic potential and clinical tractability of targets within the disease area.
• Identify transformational opportunities where projects can offer significant benefits to patients.

Program Delivery:

• Ensure quality, on-time, and on-budget delivery of studies and programs within a therapeutic area of EPU
• Design and implement experimental medicine studies to
• Oversee risk assessment across programs and ensure implementation of mitigation strategies.

Collaboration and Matrix Working:

• Collaborate with cross-functional teams with program counterparts in Advance Pipeline Unit, Commercial, Research Tech and Development organisations.
• Build and maintain networks across internal and external stakeholders, including academic institutions, CROs, and regulators.
• Represent GSK effectively in external collaborations and negotiations.

Problem Solving and Decision Making:

• Anticipate challenges and proactively develop strategies to mitigate risks.
• Make decisions balancing risk/benefit with clear understanding of project impact.
• Written and Oral Communication:
• Lead the writing and review of study-related documents and regulatory submissions.
• Communicate confidently and effectively at all levels, internally and externally.

Ways of Working:

• Champion implementation of innovative business processes and strategies to improve clinical development outcomes.

#LI-GSK

Basic Qualifications:

• Medical degree and clinical medical specialty training board qualification/registration in Respiratory Medicine/Pulmonary Medicine/Pulmonary & Critical Care.
• Experience in the global pharmaceutical/biotechnology industry in the field of respiratory medicine, with focus on COPD, including underlying biology and potential therapeutic targets
• Industry experience in respiratory/COPD clinical drug development, including experience in translational medicine and early phase drug development.
• Experience planning clinical development for an asset and/or indication.
• Experience working with multiple stakeholders on complex projects.
• Experience leading cross-functional matrix teams within a clinical development setting.
• Experience of translational medicine, clinical research methodology and principles of biostatistics to facilitate innovative and efficient designs of clinical trials and clinical development plans with clear data-driven decision rules.

Preferred Qualifications/experience:

In the addition to the above, the following will be highly desirable

• PhD in addition to medical degree and clinical medical specialty training board qualification/registration in Respiratory Medicine/Pulmonary Medicine/Pulmonary & Critical Care.
• Strong leadership skills, with proven ability to inspire high performance from cross-functional teams.
• Track record of building and maintaining strong relationships with internal and external stakeholders.
• Proven record of creative problem solving in clinical trials and projects (e.g., deriving causal confidence from novel sources, or qualifying a novel endpoint).
• Transferable leadership qualities that will support effective coaching, mentoring and development experience.
• Strong personal network across relevant scientific and clinical thought leaders, institutions and consortia in relevant therapy area.
• Future-looking and experimental track record, with demonstrable experience of tech-enable solutions in biology, translation or clinical development.�

The US annual base salary for new hires in this position ranges from $270,600 to $451,000 The US salary ranges take into account a number of factors including work location within the US market, the candidate�s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391.� The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

����

Job description
Site Name: USA - Massachusetts - Cambridge, GSK HQ, UK - Hertfordshire - Stevenage, USA - Pennsylvania - Upper Providence
Posted Date: Oct 30 2025

GSK is seeking a highly skilled and experienced Executive Medical Director to lead an exciting and expanding Hepatology program, advancing an asset through late-stage development while exploring opportunities for life-cycle management to maximize its therapeutic and commercial impact. This position reports to the VP Clinical Development, CRH, GI & Renal in the Respiratory, Immunology & Inflammation Research Unit (RIIRU) Advanced Pipeline Unit (APU).

About RIIRU:

The Respiratory, Immunology and Inflammation Research Unit (RIIRU) was formed in 2024 to identify and advance novel molecular targets with genetic associations to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two-fold. The remit of RIIRU is to identify novel targets based on human genetics, develop assets for clinical studies, and perform trials through to submission for approvals. This goal is enabled through strategic external (e.g., Flagship Pioneering, Vesalius, Muna Therapeutics and others) and GSK-internal partnerships (Research Technologies).?�

PLEASE NOTE: This career opportunity requires an on-site office presence (minimum of two days a week) in one of GSK�s US�(PA or MA) or UK (London - New Oxford Street or Stevenage) sites.

Key Responsibilities

• Strategic Leadership:�Provide medical and scientific leadership for a hepatology asset, driving strategy to achieve clinical, regulatory, and commercial milestones while ensuring alignment with GSK�s strategic priorities.
• Late-Stage Drug Development:�Oversee the design, initiation, execution, and closure of late-stage clinical trials, including Phase 3 studies, ensuring delivery of high-quality data to support regulatory approval and commercialization.
• Global Regulatory Interactions:�Lead critical regulatory activities, including dossier submissions, preparation for meetings with health authorities (e.g., FDA, EMA, PMDA), and responses to regulatory queries.
• Life-Cycle Management:�Identify, develop, and execute strategies to expand the asset beyond its primary indication, exploring significant life-cycle opportunities to maximize its therapeutic and commercial potential.
• Cross-Functional Collaboration:�Leverage significant experience working across a complex cross-functional matrix to partner with clinical, translational, commercial, regulatory, and scientific teams.
• Innovation and Competitive Intelligence:�Monitor emerging trends, competitor activities, and advancements in hepatology and related fields to identify opportunities for differentiation and strategic growth.
• Team Leadership:�Lead and mentor a high-performing team, fostering professional development, providing clear direction, and ensuring alignment with GSK�s values and objectives.
• External Representation:�Act as a key representative of GSK's RIIRU in hepatology, engaging with external stakeholders, scientific forums, and professional organizations to advance the company�s visibility and influence in this therapeutic area.

#LI-GSK

Basic Qualifications

• Medical degree and clinical medical specialty training board qualification/registration.
• Experience in the global pharmaceutical/biotechnology industry in the field of hepatology.
• Experience in clinical research and drug development, with a focus on hepatology.
• Line-management experience overseeing medical directors and/or clinical scientists as well as leading matrix teams within a clinical development setting.
• Experience in late-stage hepatology drug development, including Phase 2 and Phase 3 clinical trial design, initiation, execution, and closure.

Preferred Qualifications

• Medical degree and clinical medical specialty training board qualification/registration in Gastroenterology or Hepatology.
• Demonstrated success in life-cycle management, including identifying opportunities for indication expansion and strategic development beyond primary indications.
• Experience with regulatory interactions, including submissions, strategy meetings, and negotiations with health authorities.
• Understanding of the clinical and scientific landscape in hepatology, experience in advancing innovative therapies.
• Experience in translational medicine and biomarker development.

The US annual base salary for new hires in this position ranges from $270,600 to $451,000 The US salary ranges take into account a number of factors including work location within the US market, the candidate�s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit� GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/