2 roles available 

Role 1: Homebased Pharmacy Inspector (covering sites in Southwest London and surrounding areas)

Role 2: Homebased Pharmacy Inspector (covering sites in Southwest England, including Devon and Cornwall)

Closing date: 7 October 2026 (11.59pm)

Interview dates: TBA

Salary details: Starting from £45,891, depending on skills and experience, plus benefits and a £6,576 car allowance per annum (or £7,476 per annum for PHEV/EV drivers only)

Location: Homebased. You will be required to live in or close to the area of the job you choose to apply.

Hours: 35 hours per week, from 9.00 to 5.00, Monday to Friday

The role:

• Are you a registered Pharmacist or Pharmacy Technician with an in-depth knowledge of the GPhC’s standards and responsibilities?

• Do you have experience in the implementation and use of technology in the delivery of pharmacy services particularly in a community or hospital setting?

• Do you want to apply your knowledge and experience to provide assurance to patients and the public about the quality of pharmacy services and help drive improvement?

If so, we welcome you to apply for our fixed term contract Pharmacy Inspector vacancy…

The GPhC works to provide assurance to patients and the public that the pharmacies on our register are practising safely and effectively.

The post-holder will make an integral contribution to this aim by maintaining a programme of high-quality inspections of registered pharmacy premises through monitoring, supporting, and enforcing compliance in line with the GPhC’s standards.

Inspectors will also provide recommendations to the Registrar on the registration suitability of new 

pharmacies and work collaboratively with our Fitness to Practise team, giving valuable advice on pharmacy practice  to inform investigations into allegations of pharmacy professional’s fitness to practise.

Benefits when joining our team

In return for their commitment and enthusiasm, employees can expect a rewarding and challenging work environment, good work-life balance and workload plus an excellent benefits package that includes:

• 30 days holiday (plus bank holidays) with the option to buy an additional 5 days.

• Pension Scheme.

• Flexible working arrangements.

• Career breaks and sabbaticals.

• Life assurance, season ticket loan, bike loan and many more.

Applying for this role

If you feel you have the required experience and skills and would like to join us, please complete our application form, including the supporting statement section explaining how you meet each of the criteria for the role, and where you found out about this vacancy.

Please note that applications without a supporting statement will not be considered.

Please consult the knowledge and skills section of the job description document to help you prepare your application.

We welcome applications from all sections of the community

We are committed to promoting equality, valuing diversity and being inclusive in all our work as a health professions regulator.

Whilst we are proud to be members of the Disability Confident Scheme, you don’t have to have a disability for us to discuss reasonable adjustments. Please let us know if you need any support during the application or interview process and we will happily discuss this with you.

As part of your application for this role, please complete our equal opportunities and diversity monitoring section. This is optional and you don't have to complete it; however it provides us with useful information for monitoring and reporting purposes and is strictly confidential.

The information you provide on this form will not form part of any selection process and will not be shared with the selection panel.

Offer insight from lived experience: Share your experience of issues affecting people living with, affected by or at risk of kidney disease, to help inform activity.

Review newly created or reviewed health information: Test and review health information that will be available to patients to ensure it is easily understood and accessible.

Co-design of our health information: Help plan and design health information created by Kidney Research UK for our patient audience.

Provide feedback to campaign messaging and direction: Give feedback to any relevant campaign messaging created by the marketing and communications team to ensure the voices of those with lived experience of kidney disease are incorporated.

Provide feedback to our supporter magazine and other publications: Update is our supporter magazine, published twice a year. Here volunteers would share feedback about the magazine, and any other publications, to help improve content for our audiences.

User testing: When launching new digital projects, platforms or surveys it is often helpful for them to be tested by those who will use it to make sure they work correctly and are easy to take part in.

Advise on communications approaches: The group will meet virtually every 4 months to look at progress of the panel and discuss any upcoming projects that the marketing and communications team are working on. There will be ad hoc meetings or involvement in between these set meetings in response to marketing and communications activity.

kindly note

All reasonable, pre-agreed expenses incurred (such as travel) will be reimbursed.
You will receive:

• An induction covering the charity, its aims, and the role of the Marketing and Communications panel

• Ongoing support from your designated contact within the charity

• Relevant training to support you in your role, where needed

• Reimbursement of agreed out-of-pocket expenses for attending meetings or carrying out duties, in line with your role

Job description
Site Name: USA - Pennsylvania - Upper Providence, Durham Blackwell Street, UK – London – New Oxford Street, USA - Massachusetts - Waltham
Posted Date: Dec 19 2025

The Director, Real-World Biostatistics is a key role focused on advancing strategy and methodology in the entire course of drug/vaccine development using real-world data (RWD) within the enterprise. This position requires providing deep biostatistical expertise, strategic insight, and supporting methodological innovation to enhance the development and commercialization of pharmaceutical products, primarily in the oncology research unit (RU).

The Director will design and analyze RWD studies and other observational studies using cutting-edge biostatistical methodologies associated with causal inference and comparative effectiveness, clinical outcomes assessment, longitudinal and predictive modelling, and target trial emulation, while also mentoring staff assigned to these projects. 

Key Responsibilities:

Biostatistical and Methodologic Support:

• Lead and oversee the execution of real-world studies, ensuring methodological rigor, quality control, and regulatory adherence.

• Create and refine statistical analysis plans, conduct complex statistical analyses, and convey findings to internal and external stakeholders.

• Apply fit for purpose non-interventional statistical methods tailored to specific study objectives, ensuring robust data interpretation and insight generation.

Therapy Area Knowledge:

• Understand RU/assets to apply appropriate tools (e.g., variable definitions, code lists) and data sources and leverage hands on with RWD expertise to guide the selection and appropriate use of complex health data sets, including experience authoring technical specification documents

• Develop in-depth knowledge on the assigned asset(s) and act as senior-level RWB consultant on matrix teams

Project Management and Staff Mentorship:

• Mentor junior staff, guiding and developing their capabilities through mentorship, training, and professional growth opportunities while promoting knowledge sharing, continuous learning, and an innovative and collaborative environment.

• Lead statistical efforts for assigned projects, manage timelines, resources, quality control, and coordinate across departments (e.g. epidemiology, health economics and outcomes research, clinical).

Communication and Strategic Initiatives:

• Engage in strategic communication within the organization and with external audiences presenting statistical analyses and insights clearly and effectively at conferences, in publications, and during key stakeholder meetings, reinforcing the value of biostatistical contributions.

Methodological Development and Innovation:

• Stay informed on industry trends, incorporate emerging biostatistical methods to enhance study designs and analytics, and participate in methodological research for the development of analytical techniques.

Regulatory Support and Compliance:

• Provide biostatistical expertise on RWD during regulatory submissions, meeting preparations, and addressing queries to ensure alignment with regulatory standards while offering statistical guidance for organizational decision-making processes.

• Stay informed with guidance documents from regulators to industry on use of RWD for regulatory decision-making

Why you?

Basic Qualifications:

• Ph.D. in Biostatistics, Statistics, Epidemiology or related disciplines with 8+ years (or Masters plus 10+ years) of working within the pharmaceutical/biotech industry (preferably in real-world evidence, epidemiology, or health outcomes functional areas)

• Experience working with drug development processes and strategies, utilizing innovative statistical skills to meet project and/or business objectives

• Experience leading pharmacoepidemiology and/or health outcomes analytics using RWD(e.g, electronic health record; insurance claims; registries) and applying observational study design and biostatistical principles to clinical/epidemiological research

• Experience in programming languages (e.g., R, Python) and applied experience with observational data.

• Experience in working according to regulatory requirements pertaining to RWD and clinical trials.

• Experience in managing projects, delivering results in matrixed environments.

• Experience in methodological research with contributions to publications in real-world data analytics.

Preferred Qualifications:

• Experience in causal inference methodology such as propensity score based approaches, doubly-robust estimations including target maximum likelihood estimation (TMLE), principal stratification/instrumental variable approaches, methods for time-varying exposures.

• Experience in time-to-event analysis in the setting of non-randomized studies

• Experience in machine learning

• Excellent communication and interpersonal skills for conveying complex statistical concepts effectively.

• Fluency in written and spoken English

#LI-GSK

• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $174,900 to $291,500.

The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.

Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job description
Site Name: UK - Hertfordshire - Stevenage, UK – London – New Oxford Street, USA - Massachusetts - Boston, USA - Pennsylvania - Upper Providence
Posted Date: Jan 13 2026

GSK is seeking a Clinical Development Medical Director - Hepatology to act as a translational leader within the Early Pipeline Unit (EPU) of the Respiratory, Immunology and Inflammation Research Unit (RIIRU). The successful individual will provide medical and scientific expertise to pre-clinical, clinical and translational studies. They will lead programs or work within project teams to conceptualize, design, plan and execute projects including first-time-in-human trials for new assets, experimental medicine studies and translational data generation. They will work cross-functionally to develop and execute clinical development plan(s) up to, and including, Proof of mechanism/Proof of concept studies. This is an exciting opportunity to bring new therapies into the clinic with a particular focus on treatments for steatotic liver disease (including MASH and ALD) and chronic Hepatitis B.

Key Accountabilities / Responsibilities:

• Drive development of clinical plans and study designs and ensure alignment with translational plans and project strategies to ensure quality execution of the clinical development plan. Will develop sections of core regulatory documents.
• Generate the data and evidence required to determine a target or medicines’ potential efficacy, safety profile, key areas of product differentiation and route to becoming a medicine with value to patients in the shortest possible timeframe
• Deliver clinical development and study timelines and endpoints, including pharmacology, mechanism and clinical efficacy endpoints, enabling key decision points and Go/No Go criteria for the CDP.
• Seek and maintain relationships with program counterparts in Biology, Translational, Commercial, Research, Regulatory, Clinical Operations, Access, Medical Affairs and Statistics.
• Contribute to the implementation and embedding of strategic initiatives and various organizational initiatives in Clinical Development

Clinical Development Strategy; Study & Program Design:

• Designs clinical development plans and study protocols across all phases of development, reflecting internal and external stakeholder input (e.g. patients, evidence generation, regulators, payors, pharmacovigilance)
• Develops clinical study protocols, amendments, investigator brochures and clinical study reports.
• Contributes to the study team discussions on indication planning, incorporates input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc) to contribute to vital deliverables including early Medicine Profile, Target Validation, Translational Plans, Candidate Selection.
• Provides effective support and oversight of R&D evidence generation activities to assure patient safety and study delivery.
• Inputs to regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.
• Provides medical monitoring and oversight of the safety of study participants on behalf of the Sponsor during the study, together with Pharmacovigilance Physician. Accountability for Medical
• Governance across the project to ensure scientific integrity and overall safety of the study subjects across the study.

Clinical Leadership:

• Actively leads the end-to-end clinical development strategy for an EPU program and may contribute to later stages. Accountable for leading the CMT on an EPU program. Serves as a clinical point of contact both internally and externally for an indication of an asset indication (i.e. Pre-POC and single indication) or for a clinical study. Represents the clinical matrix team at EDT or clinical study at CMT.
• Collaborate with cross-functional teams, including biology, translational, regulatory affairs, medical affairs, and commercial teams, to ensure cohesive and comprehensive translational and clinical development plans. Act as Clinical Lead at study level.
• Serves as the primary clinical interface with the relevant internal RIIRU/GSK review board (ie Technical Review or governance) and/or Protocol Review Board.
• Clinical evaluation of business development opportunities.
• Stays abreast of advancements in hepatology research, clinical trial methodologies, competitive environment and regulatory space to maintain GSK’s competitive edge. Identifies and highlights transformational opportunity where projects can offer highly significant benefit to patients in ways not possible with existing approaches.
• Gathers and supports the integration of inputs from across disciplines (scientific, clinical commercial, regulatory) to contribute to clinical components of the Medicine Profile. Consistently contributes to solving study and overall clinical development plan problems.
• Contributes to the implementation and embedding of strategic initiatives and various organizational initiatives in the EPU.
• Demonstrates ability to influence others at project, departmental and inter-departmental levels, as appropriate

Influencing and inspiring others, managing conflict:

• Able to consistently inspire others by setting a positive example, communicating a compelling vision, and creating an environment where team members feel valued and motivated.
• Demonstrated experience in managing conflicts effectively and independently, negotiating mutually acceptable solutions.
• Consistently achieves desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support.

Enterprise mindset and navigating ambiguity:

• Demonstrated flexibility and adaptability in changing environments, able to analyze incomplete information, identify potential risks and implications, and make informed decisions.
• Demonstrated enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.
• Embraces challenge as an opportunity for creativity and uses new learning and digital tools to create innovation in other areas
• Proactively generates ideas for innovative improvement and takes advantage of opportunities that arise; promotes environment for others to generate ideas for improvement

Why You?

Basic Qualifications:

We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

• Medical Degree required; general internal medicine or alternative experience in a relevant disease area preferred
• Completion of clinical residency and appropriate specialty training, ideally including hepatology experience
• Experience in preclinical or clinical research and development (may include postgrad experience)
• Knowledge and experience in the execution of translational studies including both generation and analysis of human translational data and/or conduct of preclinical biological experiments in relevant model systems
• Robust knowledge of hepatology specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution.
• Knowledge of regulatory requirements, Good Clinical Practice (GCP), and ethical guidelines for clinical research.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• PhD or other higher research degree
• Board certified/eligible in gastroenterology with focus in hepatology
• Experience working with global regulatory agencies and managing global clinical trials in hepatology.

• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $222,750 to $371,250.

• If you are based in another US location, the annual base salary range is $202,500 to $337,500.

The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

 

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

 

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

 

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

 

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

 

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.

 

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a  Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

 

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

 

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job description
Site Name: UK - Hertfordshire - Stevenage, UK – London – New Oxford Street, USA - Massachusetts - Boston, USA - Pennsylvania - Upper Providence
Posted Date: Jan 13 2026

GSK is seeking a Clinical Development Medical Director - Hepatology to act as a translational leader within the Early Pipeline Unit (EPU) of the Respiratory, Immunology and Inflammation Research Unit (RIIRU). The successful individual will provide medical and scientific expertise to pre-clinical, clinical and translational studies. They will lead programs or work within project teams to conceptualize, design, plan and execute projects including first-time-in-human trials for new assets, experimental medicine studies and translational data generation. They will work cross-functionally to develop and execute clinical development plan(s) up to, and including, Proof of mechanism/Proof of concept studies. This is an exciting opportunity to bring new therapies into the clinic with a particular focus on treatments for steatotic liver disease (including MASH and ALD) and chronic Hepatitis B.

Key Accountabilities / Responsibilities:

• Drive development of clinical plans and study designs and ensure alignment with translational plans and project strategies to ensure quality execution of the clinical development plan. Will develop sections of core regulatory documents.
• Generate the data and evidence required to determine a target or medicines’ potential efficacy, safety profile, key areas of product differentiation and route to becoming a medicine with value to patients in the shortest possible timeframe
• Deliver clinical development and study timelines and endpoints, including pharmacology, mechanism and clinical efficacy endpoints, enabling key decision points and Go/No Go criteria for the CDP.
• Seek and maintain relationships with program counterparts in Biology, Translational, Commercial, Research, Regulatory, Clinical Operations, Access, Medical Affairs and Statistics.
• Contribute to the implementation and embedding of strategic initiatives and various organizational initiatives in Clinical Development

Clinical Development Strategy; Study & Program Design:

• Designs clinical development plans and study protocols across all phases of development, reflecting internal and external stakeholder input (e.g. patients, evidence generation, regulators, payors, pharmacovigilance)
• Develops clinical study protocols, amendments, investigator brochures and clinical study reports.
• Contributes to the study team discussions on indication planning, incorporates input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc) to contribute to vital deliverables including early Medicine Profile, Target Validation, Translational Plans, Candidate Selection.
• Provides effective support and oversight of R&D evidence generation activities to assure patient safety and study delivery.
• Inputs to regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.
• Provides medical monitoring and oversight of the safety of study participants on behalf of the Sponsor during the study, together with Pharmacovigilance Physician. Accountability for Medical
• Governance across the project to ensure scientific integrity and overall safety of the study subjects across the study.

Clinical Leadership:

• Actively leads the end-to-end clinical development strategy for an EPU program and may contribute to later stages. Accountable for leading the CMT on an EPU program. Serves as a clinical point of contact both internally and externally for an indication of an asset indication (i.e. Pre-POC and single indication) or for a clinical study. Represents the clinical matrix team at EDT or clinical study at CMT.
• Collaborate with cross-functional teams, including biology, translational, regulatory affairs, medical affairs, and commercial teams, to ensure cohesive and comprehensive translational and clinical development plans. Act as Clinical Lead at study level.
• Serves as the primary clinical interface with the relevant internal RIIRU/GSK review board (ie Technical Review or governance) and/or Protocol Review Board.
• Clinical evaluation of business development opportunities.
• Stays abreast of advancements in hepatology research, clinical trial methodologies, competitive environment and regulatory space to maintain GSK’s competitive edge. Identifies and highlights transformational opportunity where projects can offer highly significant benefit to patients in ways not possible with existing approaches.
• Gathers and supports the integration of inputs from across disciplines (scientific, clinical commercial, regulatory) to contribute to clinical components of the Medicine Profile. Consistently contributes to solving study and overall clinical development plan problems.
• Contributes to the implementation and embedding of strategic initiatives and various organizational initiatives in the EPU.
• Demonstrates ability to influence others at project, departmental and inter-departmental levels, as appropriate

Influencing and inspiring others, managing conflict:

• Able to consistently inspire others by setting a positive example, communicating a compelling vision, and creating an environment where team members feel valued and motivated.
• Demonstrated experience in managing conflicts effectively and independently, negotiating mutually acceptable solutions.
• Consistently achieves desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support.

Enterprise mindset and navigating ambiguity:

• Demonstrated flexibility and adaptability in changing environments, able to analyze incomplete information, identify potential risks and implications, and make informed decisions.
• Demonstrated enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.
• Embraces challenge as an opportunity for creativity and uses new learning and digital tools to create innovation in other areas
• Proactively generates ideas for innovative improvement and takes advantage of opportunities that arise; promotes environment for others to generate ideas for improvement

Why You?

Basic Qualifications:

We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

• Medical Degree required; general internal medicine or alternative experience in a relevant disease area preferred
• Completion of clinical residency and appropriate specialty training, ideally including hepatology experience
• Experience in preclinical or clinical research and development (may include postgrad experience)
• Knowledge and experience in the execution of translational studies including both generation and analysis of human translational data and/or conduct of preclinical biological experiments in relevant model systems
• Robust knowledge of hepatology specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution.
• Knowledge of regulatory requirements, Good Clinical Practice (GCP), and ethical guidelines for clinical research.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• PhD or other higher research degree
• Board certified/eligible in gastroenterology with focus in hepatology
• Experience working with global regulatory agencies and managing global clinical trials in hepatology.

• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $222,750 to $371,250.

• If you are based in another US location, the annual base salary range is $202,500 to $337,500.

The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

 

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

 

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

 

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

 

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

 

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.

 

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a  Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

 

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

 

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job description
Site Name: USA - Pennsylvania - Pennsylvania Central, Stevenage, UK - London, USA - Massachusetts - Boston
Posted Date: Jan 13 2026

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D

 

GSK is seeking a Clinical Development Medical Director - Hepatology to act as a translational leader within the Early Pipeline Unit (EPU) of the Respiratory, Immunology and Inflammation Research Unit (RIIRU). The successful individual will provide medical and scientific expertise to pre-clinical, clinical and translational studies. They will lead programs or work within project teams to conceptualize, design, plan and execute projects including first-time-in-human trials for new assets, experimental medicine studies and translational data generation. They will work cross-functionally to develop and execute clinical development plan(s) up to, and including, Proof of mechanism/Proof of concept studies. This is an exciting opportunity to bring new therapies into the clinic with a particular focus on treatments for steatotic liver disease (including MASH and ALD) and chronic Hepatitis B.

Key Accountabilities / Responsibilities:

• Drive development of clinical plans and study designs and ensure alignment with translational plans and project strategies to ensure quality execution of the clinical development plan. Will develop sections of core regulatory documents.

• Generate the data and evidence required to determine a target or medicines’ potential efficacy, safety profile, key areas of product differentiation and route to becoming a medicine with value to patients in the shortest possible timeframe

• Deliver clinical development and study timelines and endpoints, including pharmacology, mechanism and clinical efficacy endpoints, enabling key decision points and Go/No Go criteria for the CDP.

• Seek and maintain relationships with program counterparts in Biology, Translational, Commercial, Research, Regulatory, Clinical Operations, Access, Medical Affairs and Statistics.

• Contribute to the implementation and embedding of strategic initiatives and various organizational initiatives in Clinical Development

Clinical Development Strategy; Study & Program Design:

• Designs clinical development plans and study protocols across all phases of development, reflecting internal and external stakeholder input (e.g. patients, evidence generation, regulators, payors, pharmacovigilance)

• Develops clinical study protocols, amendments, investigator brochures and clinical study reports.

• Contributes to the study team discussions on indication planning, incorporates input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc) to contribute to vital deliverables including early Medicine Profile, Target Validation, Translational Plans, Candidate Selection.

• Provides effective support and oversight of R&D evidence generation activities to assure patient safety and study delivery.

• Inputs to regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.

• Provides medical monitoring and oversight of the safety of study participants on behalf of the Sponsor during the study, together with Pharmacovigilance Physician. Accountability for Medical

• Governance across the project to ensure scientific integrity and overall safety of the study subjects across the study.

Clinical Leadership:

• Actively leads the end-to-end clinical development strategy for an EPU program and may contribute to later stages. Accountable for leading the CMT on an EPU program. Serves as a clinical point of contact both internally and externally for an indication of an asset indication (i.e. Pre-POC and single indication) or for a clinical study. Represents the clinical matrix team at EDT or clinical study at CMT.

• Collaborate with cross-functional teams, including biology, translational, regulatory affairs, medical affairs, and commercial teams, to ensure cohesive and comprehensive translational and clinical development plans. Act as Clinical Lead at study level.

• Serves as the primary clinical interface with the relevant internal RIIRU/GSK review board (ie Technical Review or governance) and/or Protocol Review Board.

• Clinical evaluation of business development opportunities.

• Stays abreast of advancements in hepatology research, clinical trial methodologies, competitive environment and regulatory space to maintain GSK’s competitive edge. Identifies and highlights transformational opportunity where projects can offer highly significant benefit to patients in ways not possible with existing approaches.

• Gathers and supports the integration of inputs from across disciplines (scientific, clinical commercial, regulatory) to contribute to clinical components of the Medicine Profile. Consistently contributes to solving study and overall clinical development plan problems.

• Contributes to the implementation and embedding of strategic initiatives and various organizational initiatives in the EPU.

• Demonstrates ability to influence others at project, departmental and inter-departmental levels, as appropriate

Influencing and inspiring others, managing conflict:

• Able to consistently inspire others by setting a positive example, communicating a compelling vision, and creating an environment where team members feel valued and motivated.

• Demonstrated experience in managing conflicts effectively and independently, negotiating mutually acceptable solutions.

• Consistently achieves desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support.

Enterprise mindset and navigating ambiguity:

• Demonstrated flexibility and adaptability in changing environments, able to analyze incomplete information, identify potential risks and implications, and make informed decisions.

• Demonstrated enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.

• Embraces challenge as an opportunity for creativity and uses new learning and digital tools to create innovation in other areas

• Proactively generates ideas for innovative improvement and takes advantage of opportunities that arise; promotes environment for others to generate ideas for improvement

Why You?

Basic Qualifications:

We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

• Medical Degree required; general internal medicine or alternative experience in a relevant disease area preferred

• Completion of clinical residency and appropriate specialty training, ideally including hepatology experience

• Experience in preclinical or clinical research and development (may include postgrad experience)

• Knowledge and experience in the execution of translational studies including both generation and analysis of human translational data and/or conduct of preclinical biological experiments in relevant model systems

• Robust knowledge of hepatology specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution.

• Knowledge of regulatory requirements, Good Clinical Practice (GCP), and ethical guidelines for clinical research.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• PhD or other higher research degree

• Board certified/eligible in gastroenterology with focus in hepatology

• Experience working with global regulatory agencies and managing global clinical trials in hepatology.

• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $222,750 to $371,250.

• If you are based in another US location, the annual base salary range is $202,500 to $337,500.

The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.

Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job description
Site Name: USA - Pennsylvania - Pennsylvania Central, Stevenage, UK - London, USA - Massachusetts - Boston
Posted Date: Jan 13 2026

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D

 

GSK is seeking a Clinical Development Medical Director - Hepatology to act as a translational leader within the Early Pipeline Unit (EPU) of the Respiratory, Immunology and Inflammation Research Unit (RIIRU). The successful individual will provide medical and scientific expertise to pre-clinical, clinical and translational studies. They will lead programs or work within project teams to conceptualize, design, plan and execute projects including first-time-in-human trials for new assets, experimental medicine studies and translational data generation. They will work cross-functionally to develop and execute clinical development plan(s) up to, and including, Proof of mechanism/Proof of concept studies. This is an exciting opportunity to bring new therapies into the clinic with a particular focus on treatments for steatotic liver disease (including MASH and ALD) and chronic Hepatitis B.

Key Accountabilities / Responsibilities:

• Drive development of clinical plans and study designs and ensure alignment with translational plans and project strategies to ensure quality execution of the clinical development plan. Will develop sections of core regulatory documents.

• Generate the data and evidence required to determine a target or medicines’ potential efficacy, safety profile, key areas of product differentiation and route to becoming a medicine with value to patients in the shortest possible timeframe

• Deliver clinical development and study timelines and endpoints, including pharmacology, mechanism and clinical efficacy endpoints, enabling key decision points and Go/No Go criteria for the CDP.

• Seek and maintain relationships with program counterparts in Biology, Translational, Commercial, Research, Regulatory, Clinical Operations, Access, Medical Affairs and Statistics.

• Contribute to the implementation and embedding of strategic initiatives and various organizational initiatives in Clinical Development

Clinical Development Strategy; Study & Program Design:

• Designs clinical development plans and study protocols across all phases of development, reflecting internal and external stakeholder input (e.g. patients, evidence generation, regulators, payors, pharmacovigilance)

• Develops clinical study protocols, amendments, investigator brochures and clinical study reports.

• Contributes to the study team discussions on indication planning, incorporates input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc) to contribute to vital deliverables including early Medicine Profile, Target Validation, Translational Plans, Candidate Selection.

• Provides effective support and oversight of R&D evidence generation activities to assure patient safety and study delivery.

• Inputs to regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.

• Provides medical monitoring and oversight of the safety of study participants on behalf of the Sponsor during the study, together with Pharmacovigilance Physician. Accountability for Medical

• Governance across the project to ensure scientific integrity and overall safety of the study subjects across the study.

Clinical Leadership:

• Actively leads the end-to-end clinical development strategy for an EPU program and may contribute to later stages. Accountable for leading the CMT on an EPU program. Serves as a clinical point of contact both internally and externally for an indication of an asset indication (i.e. Pre-POC and single indication) or for a clinical study. Represents the clinical matrix team at EDT or clinical study at CMT.

• Collaborate with cross-functional teams, including biology, translational, regulatory affairs, medical affairs, and commercial teams, to ensure cohesive and comprehensive translational and clinical development plans. Act as Clinical Lead at study level.

• Serves as the primary clinical interface with the relevant internal RIIRU/GSK review board (ie Technical Review or governance) and/or Protocol Review Board.

• Clinical evaluation of business development opportunities.

• Stays abreast of advancements in hepatology research, clinical trial methodologies, competitive environment and regulatory space to maintain GSK’s competitive edge. Identifies and highlights transformational opportunity where projects can offer highly significant benefit to patients in ways not possible with existing approaches.

• Gathers and supports the integration of inputs from across disciplines (scientific, clinical commercial, regulatory) to contribute to clinical components of the Medicine Profile. Consistently contributes to solving study and overall clinical development plan problems.

• Contributes to the implementation and embedding of strategic initiatives and various organizational initiatives in the EPU.

• Demonstrates ability to influence others at project, departmental and inter-departmental levels, as appropriate

Influencing and inspiring others, managing conflict:

• Able to consistently inspire others by setting a positive example, communicating a compelling vision, and creating an environment where team members feel valued and motivated.

• Demonstrated experience in managing conflicts effectively and independently, negotiating mutually acceptable solutions.

• Consistently achieves desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support.

Enterprise mindset and navigating ambiguity:

• Demonstrated flexibility and adaptability in changing environments, able to analyze incomplete information, identify potential risks and implications, and make informed decisions.

• Demonstrated enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.

• Embraces challenge as an opportunity for creativity and uses new learning and digital tools to create innovation in other areas

• Proactively generates ideas for innovative improvement and takes advantage of opportunities that arise; promotes environment for others to generate ideas for improvement

Why You?

Basic Qualifications:

We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

• Medical Degree required; general internal medicine or alternative experience in a relevant disease area preferred

• Completion of clinical residency and appropriate specialty training, ideally including hepatology experience

• Experience in preclinical or clinical research and development (may include postgrad experience)

• Knowledge and experience in the execution of translational studies including both generation and analysis of human translational data and/or conduct of preclinical biological experiments in relevant model systems

• Robust knowledge of hepatology specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution.

• Knowledge of regulatory requirements, Good Clinical Practice (GCP), and ethical guidelines for clinical research.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• PhD or other higher research degree

• Board certified/eligible in gastroenterology with focus in hepatology

• Experience working with global regulatory agencies and managing global clinical trials in hepatology.

• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $222,750 to $371,250.

• If you are based in another US location, the annual base salary range is $202,500 to $337,500.

The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.

Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job description
Site Name: USA - Pennsylvania - Upper Providence, GSK HQ, UK - Hertfordshire - Stevenage, USA - Massachusetts - Waltham
Posted Date: Mar 9 2026

GSK is seeking a highly skilled Senior Medical Director, Clinical Development, for GSK's Hepatology group to provide clinical and scientific leadership for potential new, established and emerging indications for assets in clinical development with a strong focus on steatotic liver disease (SLD), including alcohol-associated liver disease (ALD). You will work with project teams to plan and ensure delivery of clinical research and development activities and establish efficient collaboration throughout all stages of development. You will report to the Senior Director/Clinical Development Lead for an asset in the SLD therapeutic area. This role is pivotal in driving GSK’s mission to deliver transformative medicines to patients, ensuring clinical excellence, regulatory compliance, and operational efficiency. The successful candidate will not only deliver results but also inspire and empower teams to achieve exceptional outcomes.

About RIIRU:

The Respiratory, Immunology and Inflammation Research Unit (RIIRU) was formed in 2024 to identify and advance novel molecular targets with genetic associations to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two-fold. The remit of RIIRU is to identify novel targets based on human genetics, develop assets for clinical studies, and perform trials through to submission for approvals. This goal is enabled through strategic external (e.g., Flagship Pioneering, Vesalius, Muna Therapeutics and others) and GSK-internal partnerships (Research Technologies).  

PLEASE NOTE: This career opportunity requires an on-site office presence (minimum of two days a week) at one of GSK’s US (PA or MA) or UK (Stevenage or London HQ) sites.

Key Responsibilities:

• Contribute to the clinical development strategy for a drug or program.

• Ensure execution of clinical development plans (CDP) for product(s) and/or indication(s) and provide strategic oversight and management of clinical trials.
• Lead clinical development activities from a therapeutic area and clinical trial perspective, including:
  • Provide clinical and medical oversight of ongoing clinical trials
  • Lead clinical trials and asset-level activities in a matrix team structure
• Identify and highlight transformational opportunities where projects can offer highly significant benefit to patients.
• Contribute to development of the Integrated Evidence Strategy (IES). Integrate scientific rationale, regulatory requirements, product development plans, and commercial goals to optimize asset indications and trials.
• Contribute to clinical development discussions and teams at global regulatory interactions. Draft clinical components of global regulatory submissions/files (e.g., IND, NDA, BLA, MAA), including briefing documents, presentations, and responses to regulatory questions.
• Promote innovative methodologies and processes including digital tools, encouraging others to think differently and adopt new ways of working.
• Stay abreast of advancements in therapeutic area research, clinical trial methodologies, competitive environment, and regulatory space to maintain GSK’s competitive edge.

#LI-GSK

Basic Qualifications:

• Medical degree and clinical medical specialty training board qualification/registration in Internal Medicine or Primary Medical.  
• Experience in the global pharmaceutical/biotechnology industry in the field of Hepatology.
• Experience in clinical research and drug development, with a focus on SLD, including ALD and MASH.
• Experience in late-stage Hepatology drug development, including Phase 2 and Phase 3 clinical trial design, initiation, execution, and closure.
• Experience in medical monitoring activities and oversight.
• Experience in leading regulatory submissions and managing global clinical trials.
• Experience with ICH and GCP guidelines and regulatory requirements
• Matrix team experience within a clinical development setting.

Preferred Qualifications:

• Medical degree and clinical medical specialty training board qualification/registration in Hepatology/Gastroenterology, Endocrinology or Nephrology.
• Thorough understanding of SLD, including ALD and MASH, the underlying biology and potential therapeutic targets.
• Solid understanding of needs and priorities of regulators, payers and prescribers in relevant global market(s).
• Track record of building and maintaining strong relationships with internal and external stakeholders.
• Demonstrated strong problem-solving skills and innovative thinking. Anticipate potential challenges, develop strategic approaches, and effectively communicate uncertainty to stakeholders while guiding teams through unclear circumstances.
• Have an enterprise mindset by identifying opportunities for synergy across the organization.
• Ability to use strategic thinking to analyze, interpret, and critically evaluate complex data and information. Anticipate obstacles and identify innovative solutions to ensure timely delivery of evidence that supports regulatory approvals and patient benefit.
• Navigate ambiguity by anticipating regulatory challenges and proactively addressing issues.
• Experience of clinical research methodology and principles of biostatistics to facilitate innovative and efficient designs of clinical trials and clinical development plans with clear data-driven decision rules.

• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $284,625 to $474,375.

The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/