GSK
London
Associate Director – MSAT External Supply Drug Product
Manufacturing Science and Technology
Site Name: UK – London – New Oxford Street, Poznan Grunwaldzka, UK - Hertfordshire - Ware
Posted Date: Feb 23 2026
Associate Director – MSAT External Supply Drug Product
Closing Date: 9th March 2026 (COB)
Business Introduction
We manufacture and supply reliable, high-quality medicines and vaccines to meet patients’ needs and drive our performance.
Our network of 37 medicines and vaccines manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it’s vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply.
We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.
Position Summary
The Associate Director – MSAT External Supply Drug Product is responsible for leading a team ES Technical Managers, delivering strategic technical oversight and developing team capability within Contract Manufacturing Organisations (CMOs). This role ensures reliable product supply, oversees technical lifecycle management, and guarantees high-quality execution of MSAT activities, all in accordance with GSK’s manufacturing standards and Product Control Strategy. Additionally, the Associate Director is accountable for technical governance, risk management, cross-functional collaboration, and providing the necessary technical support to maintain compliant, effective, and continuously improving manufacturing processes throughout the ES network.
This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:
- Lead, coach, and develop a diverse team of ES Technical Managers, building capability in MSAT, regulatory expectations, and cross‑functional ways of working while fostering a high‑performance, inclusive culture.
- Provide strategic oversight and governance of CMO technical activities, ensuring alignment with GSK MSAT standards, regulatory requirements, and strong management of process performance, deviations, CAPAs, and technical risks.
- Oversee product lifecycle execution, including technology transfers, scale‑up, PPQ validation, new product introductions, and ongoing technical support to ensure uninterrupted, compliant supply.
- Build strong partnerships with CMOs and drive effective cross‑functional engagement with SRM, Procurement, QA, and Regulatory to enable issue resolution and technical objectives.
- Ensure robust risk management and compliance through routine risk assessments, high‑quality investigations, root‑cause analysis, mitigation actions, and closure of technical compliance gaps at CMOs.
Why You?
Working arrangement
- This is a global role, you can work from any key GSC site.
- The role is hybrid, with a regular on-site presence required for operational leadership.
Basic Qualification
We are seeking professionals with the following required skills and qualifications to help us achieve our goals:
- Bachelors/Honours degree, or equivalent, in an appropriate scientific or engineering discipline.
- Extensive experience in MSAT, Technical Operations, Process Engineering, or equivalent technical leadership roles in the pharmaceutical industry.
- Deep understanding of multiple dose forms, manufacturing technologies, and CMO operations.
- Proven experience leading technical teams and managing complex technical portfolios.
- Strong knowledge of regulatory requirements (FDA, EMA, MHRA), QMS, validation, and lifecycle management.
Preferred Qualification
If you have the following characteristics, it would be a plus:
- Advanced degree (MSc) in a relevant discipline.
- Familiarity with continuous improvement methods such as Lean or Six Sigma.
- Experience with risk assessment tools (for example FMEA) and Quality by Design approaches.
- Experience managing external partners, contract manufacturers or multi-site transfers.
- Experience with digital tools for process monitoring, data analysis or knowledge management.
What we value in you
- You use practical science and clear judgement to solve problems.
- You work openly and respectfully with colleagues and partners.
- You take accountability and communicate clearly to deliver for patients.
- You look for learning and growth and help others develop their skills.
- You influence positive change while keeping quality and safety front of mind.
How to apply
Please apply and tell us briefly how your experience meets the responsibilities and qualifications. We look forward to hearing from you.
More detailed information on the total reward package applicable to your role will be supplied during the recruitment process. Salary ranges for other locations are shown because some markets have pay transparency laws that require salary information on job postings, and those locations are potential job sites for this role. If salary ranges are not displayed in the job posting for a specific location or country, the relevant compensation will be discussed during the recruitment process. Please note salaries vary by country based on the market rate for the role.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.
Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
GSK
London
Supply Manager
Supply Chain & Logistics
Site Name: UK – London – New Oxford Street
Posted Date: Feb 27 2026
Supply Manager
Closing Date: 13th March 2026 (COB)
Business Introduction
We manufacture and supply reliable, high-quality medicines and vaccines to meet patients’ needs and drive our performance.
Our network of 37 medicines and vaccines manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it’s vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply.
We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.
Position Summary
You will lead day-to-day supply planning and execution for assigned products and site(s). You will work closely with manufacturing, logistics, procurement, and commercial teams to make sure supply meets demand. We value clear communicators who solve problems simply and act with integrity. This role offers career growth, meaningful impact on patient outcomes, and the chance to work across science, technology and talent to get ahead of disease together.
Responsibilities
This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:
- Own end-to-end supply planning and inventory management to meet customer and business needs.
- Create and maintain supply plans that balance demand, capacity and inventory targets.
- Coordinate cross-functional teams to resolve supply issues and implement sustainable solutions.
- Track supply performance and drive continuous improvement using clear metrics and reporting.
- Manage risks to supply continuity and support change management for product or process changes.
- Communicate plans and escalations clearly to stakeholders and leadership.
Why You?
Basic Qualification
We are seeking professionals with the following required skills and qualifications to help us achieve our goals:
- Degree in supply chain, engineering, business or related field, or equivalent experience.
- Experience in supply planning, inventory management, or production planning.
- Strong analytical skills with experience using planning tools or ERP systems.
- Clear, concise communication skills and ability to work with multi-disciplinary teams.
- Problem-solving mindset with a focus on delivering practical solutions.
- Right to work in the United Kingdom.
Preferred Qualification
If you have the following characteristics, it would be a plus:
- Experience in regulated industries such as pharmaceuticals, biotech or healthcare.
- Experience with SAP or other major ERP systems and advanced Excel skills.
- Knowledge of demand planning, S&OP (Sales and Operations Planning) or similar processes.
- Proven track record of driving process improvements and cost optimisation.
- Experience working in hybrid or global team environments.
- Relevant professional certification in supply chain or operations (e.g., APICS).
Working Pattern
This role is offered as a hybrid position with a mix of office and site-based work. Exact days on site will be agreed with your manager to meet team and site needs.
What we offer
You will join a team focused on purpose and collaboration. You will receive opportunities for learning and development and support to grow your career. You will work in an environment that values inclusion and treats people fairly.
How to apply
If this role excites you, we encourage you to apply. Tell us how your experience matches the responsibilities and why you want to join our team. We review applications as they arrive and will contact candidates who best match the role.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.
Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
GSK
London
Executive Medical Director, Clinical Development, Advanced Pipeline Unit (APU) Respiratory
Medical and Clinical
GSK is seeking a highly skilled Executive Medical Director, Clinical Development, APU Respiratory to provide clinical and scientific leadership for potential new, established and emerging indications for assets in clinical development with a strong focus on Interstitial Lung Diseases (ILD) including Idiopathic pulmonary Fibrosis (IPF), Progressive Pulmonary Fibrosis (PPF) and autoimmune associated ILDs including connective tissue disease Associated ILD (CTD-ILD). You will work with project teams to plan and ensure delivery of clinical research and development activities and establish efficient collaboration throughout all stages of development. You will report to the Vice President, Clinical Research Head in Respiratory. This role is pivotal in driving GSK’s mission to deliver transformative medicines to patients, ensuring clinical excellence, regulatory compliance, and operational efficiency. The successful candidate will not only deliver results but also inspire and empower teams to achieve exceptional outcomes.
About RIIRU:
The Respiratory, Immunology and Inflammation Research Unit (RIIRU) was formed in 2024 to identify and advance novel molecular targets with genetic associations to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two-fold. The remit of RIIRU is to identify novel targets based on human genetics, develop assets for clinical studies, and perform trials through to submission for approvals. This goal is enabled through strategic external (e.g., Flagship Pioneering, Vesalius, Muna Therapeutics and others) and GSK-internal partnerships (Research Technologies).
- in conversation with Tonya Winders, President and CEO of the Global Allergy and Airways Patient Platform, and Dr. Jean Wright, CEO of the COPD foundation
- Go Behind the Science with our new article featuring Dr Kaivan Khavandi, as he talks about the importance of our respiratory innovation for COPD patients
- Read more from Tony Wood as he explains the importance of prevention in respiratory care
- Read our curtain raiser press release summarizing our key data
PLEASE NOTE: This career opportunity requires an on-site office presence (minimum of two days a week) in one of GSK’s US (PA or MA) or UK (London - New Oxford Street or Stevenage) sites.
Key Responsibilities:
- Lead the clinical development strategy from a drug or program including accountability for the clinical components of the Target Medicine Profile (TMP) and leadership of the clinical matrix team (CMT). Ensure cohesive and comprehensive clinical development plans (CDP) for product(s) and/or indication(s) and provide strategic oversight and management of clinical trials. Identify and highlight transformational opportunities where projects can offer highly significant benefit to patients.
- Contribute to development of the Integrated Evidence Strategy (IES), including oversight of the CDP and its component clinical trials. Integrate scientific rationale, regulatory requirements, product development plans, and commercial goals to optimize asset indications and programs.
- Drive clinical development timelines for complex assets with clear decision points, risk/cost analyses, and Go/No Go criteria. Lead probability of technical success PTRS evaluations and assess study/project risk-benefit, implementing mitigation strategies as needed.
- Foster collaboration with Commercial, Regulatory, Clinical Operations, Medical Affairs, and Statistics teams. Act as the clinical point of contact for senior management, matrix teams, and external stakeholders, including regulators, payors, CROs, consultants, and investigators.
- Lead clinical development discussions and teams at global regulatory interactions. Draft clinical components of global regulatory submissions/files (e.g., IND, NDA, BLA, MAA), including briefing documents, presentations, and responses to regulatory questions.
- Manage technical and leadership development of Clinical Development staff via direct line management, mentoring and coaching across the organisation.
- Drive strategic initiatives, business development activities, and organizational initiatives in Clinical Development. Promote innovative methodologies and processes including digital tools, encouraging others to think differently and adopt new ways of working.
- Stay abreast of advancements in therapeutic area research, clinical trial methodologies, competitive environment, and regulatory space to maintain GSK’s competitive edge.
#LI-GSK
Basic Qualifications:
- Medical degree and clinical medical specialty training board qualification/registration.
- Experience in the global pharmaceutical/biotechnology industry in the field of Interstitial Lung Diseases.
- Experience in Idiopathic pulmonary Fibrosis (IPF), Progressive Pulmonary Fibrosis (PPF) and autoimmune associated ILDs including connective tissue disease Associated ILD (CTD-ILD).
- Experience in clinical research and drug development, with a focus on Interstitial Lung Diseases.
- Experience in late-stage Lung Disease drug development, including Phase 2 and Phase 3 clinical trial design, initiation, execution, and closure.
- Experience in leading NDA, BLA, or MAA submissions and managing global clinical trials.
- Experience of clinical research methodology and principles of biostatistics to facilitate innovative and efficient designs of clinical trials and clinical development plans with clear data-driven decision rules.
- Line-management experience overseeing medical directors and/or clinical scientists as well as leading matrix teams within a clinical development setting.
Preferred Qualifications:
- Medical degree and clinical medical specialty training board qualification/registration in Pulmonary Medicine/Pulmonary & Critical Care.
- Thorough understanding of respiratory diseases, underlying biology and potential therapeutic targets.
- Robust knowledge of ICH and GCP guidelines, regulatory and reimbursement data requirements
- Solid understanding of needs and priorities of regulators, payers and prescribers in relevant global market(s).
- Track record of building and maintaining strong relationships with internal and external stakeholders.
- Demonstrated strong problem-solving skills and innovative thinking. Anticipate potential challenges, develop strategic approaches, and effectively communicate uncertainty to stakeholders while guiding teams through unclear circumstances.
- Have an enterprise mindset by identifying opportunities for synergy across the organization.
- Ability to use strategic thinking to analyze, interpret, and critically evaluate complex data and information. Anticipate obstacles and identify innovative solutions to ensure timely delivery of evidence that supports regulatory approvals and patient benefit.
- Navigate ambiguity by anticipating regulatory challenges and proactively addressing issues.
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.
Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
GSK
London
Country Study Manager (Local Delivery Lead)
Medical and Clinical
Site Name: UK – London – New Oxford Street
Posted Date: Feb 26 2026
We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.
We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.
Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK
Country Study Manager (Local Delivery Lead)
We are seeking a Local Delivery Lead (LDL) to provide leadership and manage the activities of operational planning and delivery of Phase I-IV clinical trials in a specific country or cluster of countries; across all therapy areas (Rx and Vx) to the required quality standards, GSK written standards, local regulations and ICH GCP.
Responsibilities
This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:
- Leadership & Team Management: Provides matrix leadership and comprehensive project management to the local study team. Coordinates cross-functional experts, vendor staff, and external clinical site personnel from study planning through execution. Responsible for fostering collaboration, evaluating team performance, and delivering feedback to line management when necessary.
- Operational Oversight & Communication: Acts as the primary operational link between central and local study teams, medical, and regulatory staff. Facilitates alignment on feasibility, site selection, and local requirements. Ensuring that study systems (e.g., TMF) are complete and accurate, and progress is effectively reported to stakeholders.
- Delivery & Quality Assurance: Oversees that critical study timelines, recruitment targets, patient recruitment cycle times, data integrity, and audit quality are forecasted, monitored, and achieved. Provides troubleshooting and problem resolution support, identifies risks, and escalates issues as needed to maintain productive, efficient study delivery.
- Compliance & Documentation: Ensures all regulatory requirements are met by preparing and coordinating submissions of Clinical Study Applications and local Informed Consent Forms to Regulatory Authorities (RA) and Ethics Committees (ECs). Maintains ongoing communication and assists with audits and inspections of local clinical operations and study sites.
- Budget, Contracts & Monitoring: Estimates, tracks, and delivers against local study budgets. Advises on contract development with sites, CROs, and vendors, participates in negotiations, reviews and approves monitoring visit reports, and verifies that monitoring activities are completed according to plan. Supports financial and contractual compliance throughout the study lifecycle.
- Continuous Learning: Acquires and maintains knowledge related to study compounds, protocols, disease area pathology, local treatment guidelines, and healthcare system requirements. Continuously develops skills in GCP, SOPs, monitoring, site and project management, and shares best practices.
Why you?
Basic Qualifications & Skills:
We are looking for professionals with these required skills to achieve our goals:
- Bachelor’s degree or equivalent in a science‑related field (e.g., life sciences, medicine, clinical research, pharmacy).
- Solid operational knowledge of clinical research with experience in all stages of study lifecycle (start-up, recruitment and close out) and understanding of R&D and drug/vaccine development process.
- Demonstrated strength in problem‑solving, negotiation, conflict resolution, and stakeholder management in a matrix environment.
- Excellent communication and leadership skills, with the ability to collaborate effectively.
- Excellent planning, organisational, and project‑management skills, with the ability to operate effectively in a dynamic, fast‑changing environment.
- Strong knowledge of GCP/ICH and country‑specific regulations.
Preferred Qualifications & Skills:
Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:
- Experience in oncology and/or respiratory therapeutic areas.
- Ability to lead cross-functional teams and manage external partnerships.
- Master of Science, PhD or equivalent coupled with previous project management experience.
Closing Date for Applications – 8th March 2026
Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Working Model and Location: This role is based in the United Kingdom. The role follows a hybrid working model. You will attend the office for collaboration and key meetings. You will work remotely for focused tasks as agreed with your manager.
#LI-GSK
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive.
We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.
Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the Link where you will find answers to multiple questions we receive
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
GSK
London
Vice President, Medicine Development Leader - Renal
Science and Technology
Site Name: USA - Massachusetts - Waltham, GSK HQ, UK - Hertfordshire - Stevenage, USA - Pennsylvania - Upper Providence
Posted Date: Feb 17 2026
GSK is seeking a highly skilled Vice President, Medicine Development Leader (MDL), to strategically lead the optimal global development of a renal medicine at an asset level, acting as the single point of accountability for the medicine from clinical Proof of Concept (PoC) to Approval in the first major market(s).
By working with the various stakeholders across GSK’s Medicine Development matrix (R&D, Manufacturing, Commercial, etc.), you will define the strategic vision and operational plan for the medicine, aligning it with the overall organizational strategy. You will create and lead the matrixed Medicine Development Team (MDT), which is responsible for representing the various disciplines required to optimally deliver the development of the medicine including Clinical Development, Medical, Commercial and Manufacturing, amongst others. The Vice President, MDL reports to the SVP & Head Advanced Pipeline Unit- Respiratory, Immunology and Inflammation Research Unit.
About RIIRU:
The Respiratory, Immunology and Inflammation Research Unit (RIIRU) was formed in 2024 to identify and advance novel molecular targets with genetic associations to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two-fold. Our core therapeutic areas include Respiratory, Hepatology, Nephrology, Neurodegeneration and Rheumatology. The remit of RIIRU is to identify novel targets based on human genetics, develop assets for clinical studies, and perform trials through to submission for approvals. This goal is enabled through strategic external (e.g., Flagship Pioneering, Vesalius, Muna Therapeutics and others) and GSK-internal partnerships (Research Technologies).
PLEASE NOTE: This career opportunity requires an on-site office presence (minimum of two days a week) in one of GSK’s US (PA or MA) or UK (London - New Oxford Street or Stevenage) sites.
Key Responsibilities:
- Act as a single point of accountability in GSK for all aspects of a medicine being developed globally, from proof of clinical activity (POC) to Approval in all major market(s)
- Work closely with the Early Development Lead (EDL) and Medicine Commercial Lead (MCL) to ensure a smooth transition of the lead indication(s) from the EDL upon achievement of clinical PoC and to the MCL upon Approval in first major market(s)
- Post-approval, provide key support to the Medicine Commercial Team (MCT) in the first major markets ensuring the MDT provides optimal support to registration, including Post-Marketing Requirements (PMRs) and life cycle management (LCM) in the major markets
- Work with the functional line Heads supporting RIIRU to select MDT members and lead this multi-disciplinary matrix team, supporting differentiated development for team members, owning the performance of the MDT and partnering with Line Managers to drive performance
- Partner with the Pipeline Project Manager (PPM), energize and motivate the MDT to drive a high performing team and operational delivery of the project, including setting team objectives to ensure successful project delivery, including options for acceleration, parallel indication development and smart risk-taking.
- Partner with R&D Business Development, leading the development planning for a prospective in-licensed asset by bringing together input from the relevant functions and TA experts to develop a Medicine Profile (MP) and development plans including but not limited to clinical feasibility, regulatory planning and CMC risk mitigation
- Leads the cross-functional MDT to:
- Establish a compelling vision for the medicine and Target Medicine Profile (TMP) which positions the medicine within the R&D strategy taking the competitive landscape into account, translating GSK’s strategy into asset strategy and actionable plans for multiple areas or functions
- Deliver differentiated medicines of value for patients, stakeholders and markets through an evidence package that supports regulatory approval, market access and the product’s life cycle
- Prioritize and maximize the asset’s development options including developing multiple indications
- Partner with the Global Medical Lead (GML) and MCL to develop an indication expansion and LCM plan for the asset.
- Make clear evidence-based go / no go / accelerate decisions and identify clear inflection points, based on results
- Ensure excellence in execution of all governance processes, including MDT members, on oversight of clinical studies, patient safety & pharmacovigilance, scientific engagement and promotional practices
- Enhance patient focus by incorporating the voice of the patient into development plans
- Increase visibility amongst the external communities to bring medical solutions to patients with unmet medical needs
- Embed core processes including cost efficiency, adoption of new technology, risk identification & management, compliance with policy
- Promote organizational reputation and drives asset value by engaging and negotiating with internal and external stakeholders
- Ensures quality & compliance oversight in line with R&D expectations and project needs; ensures quality of data and science
- Serves as the asset’s single point of contact and spokesperson to Senior Management, senior boards, other relevant internal governance committees and external Advisory Committees, as needed
- Delivers and manages the asset resourcing plan (people & finances), including serving as the single point for accountability for managing the asset budget to the agreed variance, working closely with the PPM and Finance Partner to do so
Basic Qualifications:
- Advanced degree including MD, PhD, PharmD, MBA, MS
- Drug development expertise in the global pharmaceutical/biotechnology industry
- Filing experience with BLA/NDA/MAA submissions as a core responsibility
- Experience in the entirety of drug development across the R&D/commercial life cycle including Discovery, late-stage Development, Regulatory, Manufacturing Medical and Commercial
- Experience in product development and/or commercialization, in late phase development (from clinical PoC onwards), clinical trial management, post-approval studies, regulatory and manufacturing compliance
- Experience leading teams in a complex, matrixed, global and multi-disciplinary organization with high accountability, minimal authority and multiple lines of reporting
- Experience working with regulators and with regulatory requirements including legal and government frameworks within and across global geographies
- Experience creating the strategy for pre- and post-marketing studies and driving the lifecycle process
- Experience building budgets and leading the strategic and budget planning process
- Experience the healthcare environment, and access in all major markets
Preferred Qualifications:
- Highly developed ethics and integrity, with demonstrated ethical medical decision-making skills
- Strong matrix leadership and motivational skills
- Ability to work collaboratively and successfully across functions – Research, Commercial, Regulatory, Global Medicine Supply, Legal, regions etc.
#LI-GSK
• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $242,250 to $403,750.The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.
If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.
Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
GSK
London
Senior Scientific Director, Clinical Development, Advanced Pipeline Unit (APU) Respiratory
Medical and Clinical
Site Name: USA - Pennsylvania - Upper Providence, UK – London – New Oxford Street, USA - Massachusetts - Boston
Posted Date: Feb 16 2026
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D
About RIIRU:
The Respiratory, Immunology and Inflammation Research Unit (RIIRU) was formed in 2024 to identify and advance novel molecular targets with genetic associations to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two-fold. The remit of RIIRU is to identify novel targets based on human genetics, develop assets for clinical studies, and perform trials through to submission for approvals. This goal is enabled through strategic external (e.g., Flagship Pioneering, Vesalius, Muna Therapeutics and others) and GSK-internal partnerships (Research Technologies).
PLEASE NOTE: This career opportunity requires an on-site office presence (minimum of two days a week) at one of GSK’s US (PA or MA) or UK (Stevenage or London HQ) sites.
Position Summary:
A Senior Scientific Director, Clinical Development is sought to provide clinical and scientific leadership for potential new, established and emerging indications for assets in clinical development with a strong focus in respiratory disease. You will work with project teams to plan and ensure delivery of clinical research and development activities and establish efficient collaboration throughout all stages of development. You will report to the Vice President, Clinical Research Head, Respiratory. This role is pivotal in driving GSK’s mission to deliver transformative medicines to patients, ensuring clinical excellence, regulatory compliance, and operational efficiency. The successful candidate will not only deliver results but also inspire and empower teams to achieve exceptional outcomes.
This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include:
- Lead the clinical development strategy from a drug or program including accountability for the clinical components of the Target Medicine Profile (TMP) and leadership of the clinical matrix team (CMT). Ensure cohesive and comprehensive clinical development plans (CDP) for product(s) and/or indication(s). Identify and highlight transformational opportunities where projects can offer highly significant benefit to patients.
- Contribute to development of the Integrated Evidence Strategy (IES), including oversight of the CDP and its component clinical trials. Integrate scientific rationale, regulatory requirements, product development plans, and commercial goals to optimize asset indications and programs, providing strategic leadership in assuring that clinical study designs are aligned with the IES and CDP.
- Drive ambitious and achievable clinical development timelines, incorporating key decision points, risk and cost analyses, and Go/No Go criteria. Lead and be accountable for the evaluation of the probability of technical success (PTRS) of clinical studies/programs. Assess risk/benefit at the study and/or project level and take action to mitigate risk where appropriate.
- Nurture and maintain relationships with counterparts in Commercial, Regulatory, Clinical Operations, Medical Affairs, and Statistics. Serve as a clinical point of contact for senior management and senior level matrix teams, across the internal matrix and positively interface and influence a broad range of external experts (e.g., regulators, payors, CROs, consultants, investigators).
- Lead clinical development discussions and teams at global regulatory interactions. Make substantial contributions to global regulatory submissions/files (e.g., IND, NDA, BLA, MAA), including briefing documents, presentations, and responses to regulatory questions.
- Manage technical and leadership development of Clinical Development staff via direct line management, mentoring and coaching across the organisation.
- Manage and contribute to the development of strategic initiatives, specific business development activities including due diligence, and organizational initiatives in Clinical Development, championing innovative methodologies and processes including digital tools and technology, encouraging others to think differently and adopt new ways of working.
- Stay abreast of advancements in therapeutic area research, clinical trial methodologies, competitive environment, and regulatory space to maintain GSK’s competitive edge.
- Excel in ambiguous situations by demonstrating strong problem-solving skills and innovative thinking. Anticipate potential challenges, develop strategic approaches, and effectively communicate uncertainty to stakeholders while guiding teams through unclear circumstances.
- Adept at identifying opportunities for synergy and innovation across the organization and influencing others to adopt an enterprise mindset.
- Use strategic thinking to analyze, interpret, and critically evaluate complex data and information. Anticipate obstacles and identify innovative solutions to ensure timely delivery of evidence that supports regulatory approvals and patient benefit.
- Skilled in understanding individual motivations and tailoring approaches to team members to drive commitment, a strong track record of inspiring and leading others to achieve exceptional results.
- Navigate ambiguity by anticipating regulatory challenges and proactively addressing issues.
Why You?
Basic Qualifications:
We are seeking professionals with the following required skills and qualifications to help us achieve our goals:
- Advanced Degree Required: PhD or PharmD
- Minimum of 5 years of experience in Respiratory clinical research and development, may include postgrad experience.
- Minimum of 3 years of experience of contributing to or leading a global clinical development program in the biopharmaceutical industry.
- Experience working with global regulatory agencies and managing global clinical trials in respiratory disease
Preferred Qualifications:
If you have the following characteristics, it would be a plus:
- MD preferred but not required
- Proven track record of successfully leading cross-functional teams and executing industry sponsored clinical trials. In-depth knowledge of regulatory requirements, Good Clinical Practice (GCP), and ethical guidelines for clinical research. Demonstrated ability to work independently to design trials to regulatory standards from concept to completion.
- Demonstrated leadership/People Management experience in clinical practice, academia and/or industry, leading line and matrix teams with a reputation of inspiring and motivating high performance
- Experience in setting and executing scientific strategy preferred.
- Experience in translational medicine preferred.
- Experience in leading NDA, BLA, or MAA submissions preferred
• If you are based in another US location, the annual base salary range is $220,500 to $367,500.
The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.
If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.
Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
GSK
Barnard Castle
Associate Director / Device Lead
Manufacturing Science and Technology
Site Name: UK - County Durham - Barnard Castle, UK - Hertfordshire - Ware
Posted Date: Mar 3 2026
The Device Lead of Global MSAT Drug Delivery and Aseptic Technology will be the Technical owner of the Device platform and be globally accountable for Device delivery into GSK Manufacturing sites from the Supply Base. The role will require flexibility and the ability to adapt to the resource needs of the business, including international travel where applicable
This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:
Be the SPOC technical SME interface between Device/Component suppliers and GSK MSAT site teams - providing device-related technical management to MSAT where required for business improvement projects and risk management activities, represent MSAT at supplier technical and project meetings.
Deliver a robust supply strategy of Device platform by collaborating with other GSK functions: Strategy, Procurement, Quality, Logistics etc including the delivery of mould tool & assembly asset validation programmers.
Lifecycle manage the Device Platform, driving Technology Transfer from R&D and maintaining throughout the Device platform life – including post-approval regulatory change management, continued process verification, and continued increase of manufacturing efficiencies and reduction of COGs
Ensure that global device/component manufacturing processes are capable, efficient and meet specification
Own and maintain the Device design including regulatory DHF/Technical file requirements to ensure a global standardization of Device supply, maintaining an overview of relevant external standards and maintain compliance with internal procedures relevant to device manufacture, supply and risk, e.g. FDA 21 CFR 820, (EU) 2017/745, Medical Device Regulation (MDR), ISO 13485, ISO 14971, and ISO 10993.
Support Device Director, Device Strategy and Device Procurement organizations on Continuous Improvement and Business projects within the Global Supply Chain (GSC) to deliver MSAT objectives.
Work cross-functionally to communicate technical global device challenges and successes and influence at all levels including the R&D and supply chain teams to ensure both technical and commercial success of drug delivery devices and integral combination products for GSK.
Drive innovation through the introduction of new and novel device technologies and/or ways of working and champion business cases for sustainable manufacturing technology implementation or other strategic projects including those related to quality by design, design for manufacturing, product and process understanding, design control, and digital data management, and analytical competency.
Perform risk management activities (e.g. risk file review/approval) when working with product and project teams. Lead risk management process as ‘risk owner’ when required.
Why you?
Basic qualifications:
Bachelor’s in engineering or a Science Degree (e.g. Process/Mechanical Engineering, Materials Science, Biomedical Engineering/ Chemistry)
Significant experience in Medical Device Development or Manufacturing environment
OR Masters Degree with 5+ years of experience in Medical Device Manufacturing environment
Experience working in a pharmaceutical and/or medical device GMP, regulatory environment, relevant ISO standards plus the specific additional legislation needs for medical devices e.g. DHF, MDR, FDA Medical Device guidance.
Preferred Qualifications:
Knowledge of pharmaceutical development activities and processes adopted by R&D relating to product development, NPS and Technology Transfer.
Good understanding to enable management of device assembly, metrology & plastics testing techniques & procedures and GSK Specification & Drawing systems
Experience leading device groups in a global matrix environment with track record of successful global asset lifecycle management.
Operate independently within their sphere of influence and work with multiple stakeholders across global business units internally and externally
Strong interpersonal and leadership skills. Committed team player prepared to work in and embrace a team-based culture.
Able to interact well with peers, subordinates, and senior personnel in scientific, quality, engineering and operational disciplines.
Strong verbal and written communication skills.
Excellent judgment. Able to priorities and decide appropriate courses of actions. Effective at implementing decisions. Proven track record.
A working understanding of data science including digital data infrastructure, visualization, and statistical analysis
Knowledge of current GMP's, ICH Guidelines and FDA QSR and EU MDR device requirements and familiar with regulatory registration processes by FDA, EMA, and MHRA.
Specialize in Regulations and ISO standards, medical device requirements and global device and combination product regulations such as 21 CFR 820, EU MDR 2017/745, ISO 13485, and ISO 14971.
Knowledge of Injection Mould Tooling Design & Processing, Device Polymers and Materials Engineering, Springs / Wire Forming, Device Testing and Lab Management, Mathematic Modelling, Device automated assembly techniques
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.
Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
GSK
London
Clinical Development Medical Director- Hepatology
Medical and Clinical
Site Name: USA - Pennsylvania - Pennsylvania Central, Stevenage, UK - London, USA - Massachusetts - Boston
Posted Date: Jan 13 2026
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D
GSK is seeking a Clinical Development Medical Director - Hepatology to act as a translational leader within the Early Pipeline Unit (EPU) of the Respiratory, Immunology and Inflammation Research Unit (RIIRU). The successful individual will provide medical and scientific expertise to pre-clinical, clinical and translational studies. They will lead programs or work within project teams to conceptualize, design, plan and execute projects including first-time-in-human trials for new assets, experimental medicine studies and translational data generation. They will work cross-functionally to develop and execute clinical development plan(s) up to, and including, Proof of mechanism/Proof of concept studies. This is an exciting opportunity to bring new therapies into the clinic with a particular focus on treatments for steatotic liver disease (including MASH and ALD) and chronic Hepatitis B.
Key Accountabilities / Responsibilities:
Drive development of clinical plans and study designs and ensure alignment with translational plans and project strategies to ensure quality execution of the clinical development plan. Will develop sections of core regulatory documents.
Generate the data and evidence required to determine a target or medicines’ potential efficacy, safety profile, key areas of product differentiation and route to becoming a medicine with value to patients in the shortest possible timeframe
Deliver clinical development and study timelines and endpoints, including pharmacology, mechanism and clinical efficacy endpoints, enabling key decision points and Go/No Go criteria for the CDP.
Seek and maintain relationships with program counterparts in Biology, Translational, Commercial, Research, Regulatory, Clinical Operations, Access, Medical Affairs and Statistics.
Contribute to the implementation and embedding of strategic initiatives and various organizational initiatives in Clinical Development
Clinical Development Strategy; Study & Program Design:
Designs clinical development plans and study protocols across all phases of development, reflecting internal and external stakeholder input (e.g. patients, evidence generation, regulators, payors, pharmacovigilance)
Develops clinical study protocols, amendments, investigator brochures and clinical study reports.
Contributes to the study team discussions on indication planning, incorporates input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc) to contribute to vital deliverables including early Medicine Profile, Target Validation, Translational Plans, Candidate Selection.
Provides effective support and oversight of R&D evidence generation activities to assure patient safety and study delivery.
Inputs to regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.
Provides medical monitoring and oversight of the safety of study participants on behalf of the Sponsor during the study, together with Pharmacovigilance Physician. Accountability for Medical
Governance across the project to ensure scientific integrity and overall safety of the study subjects across the study.
Clinical Leadership:
Actively leads the end-to-end clinical development strategy for an EPU program and may contribute to later stages. Accountable for leading the CMT on an EPU program. Serves as a clinical point of contact both internally and externally for an indication of an asset indication (i.e. Pre-POC and single indication) or for a clinical study. Represents the clinical matrix team at EDT or clinical study at CMT.
Collaborate with cross-functional teams, including biology, translational, regulatory affairs, medical affairs, and commercial teams, to ensure cohesive and comprehensive translational and clinical development plans. Act as Clinical Lead at study level.
Serves as the primary clinical interface with the relevant internal RIIRU/GSK review board (ie Technical Review or governance) and/or Protocol Review Board.
Clinical evaluation of business development opportunities.
Stays abreast of advancements in hepatology research, clinical trial methodologies, competitive environment and regulatory space to maintain GSK’s competitive edge. Identifies and highlights transformational opportunity where projects can offer highly significant benefit to patients in ways not possible with existing approaches.
Gathers and supports the integration of inputs from across disciplines (scientific, clinical commercial, regulatory) to contribute to clinical components of the Medicine Profile. Consistently contributes to solving study and overall clinical development plan problems.
Contributes to the implementation and embedding of strategic initiatives and various organizational initiatives in the EPU.
Demonstrates ability to influence others at project, departmental and inter-departmental levels, as appropriate
Influencing and inspiring others, managing conflict:
Able to consistently inspire others by setting a positive example, communicating a compelling vision, and creating an environment where team members feel valued and motivated.
Demonstrated experience in managing conflicts effectively and independently, negotiating mutually acceptable solutions.
Consistently achieves desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support.
Enterprise mindset and navigating ambiguity:
Demonstrated flexibility and adaptability in changing environments, able to analyze incomplete information, identify potential risks and implications, and make informed decisions.
Demonstrated enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.
Embraces challenge as an opportunity for creativity and uses new learning and digital tools to create innovation in other areas
Proactively generates ideas for innovative improvement and takes advantage of opportunities that arise; promotes environment for others to generate ideas for improvement
Why You?
Basic Qualifications:
We are seeking professionals with the following required skills and qualifications to help us achieve our goals:
Medical Degree required; general internal medicine or alternative experience in a relevant disease area preferred
Completion of clinical residency and appropriate specialty training, ideally including hepatology experience
Experience in preclinical or clinical research and development (may include postgrad experience)
Knowledge and experience in the execution of translational studies including both generation and analysis of human translational data and/or conduct of preclinical biological experiments in relevant model systems
Robust knowledge of hepatology specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution.
Knowledge of regulatory requirements, Good Clinical Practice (GCP), and ethical guidelines for clinical research.
Preferred Qualifications:
If you have the following characteristics, it would be a plus:
PhD or other higher research degree
Board certified/eligible in gastroenterology with focus in hepatology
Experience working with global regulatory agencies and managing global clinical trials in hepatology.
• If you are based in another US location, the annual base salary range is $202,500 to $337,500.
The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.
If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.
Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
