The Onyx Research Data Tech organization represents a major investment by GSK R&D and Digital & Tech, designed to deliver a step-change in our ability to leverage data, knowledge, and prediction to find new medicines. We are a full-stack shop consisting of product and portfolio leadership, data engineering, infrastructure and DevOps, data / metadata / knowledge platforms, and AI/ML and analysis platforms, all geared toward:

• Building a next-generation data experience for GSK�s scientists, engineers, and decision-makers, increasing productivity and reducing time spent on �data mechanics�

• Providing best-in-class AI/ML and data analysis environments to accelerate our predictive capabilities and attract top-tier talent

• Aggressively engineering our data at scale to unlock the value of our combined data assets and predictions in real-time

Onyx Product Management is at the heart of our mission, ensuring that everything from our infrastructure, to platforms, to end-user facing data assets and environments is designed to maximize our impact on R&D. The Product Management team partners with R&D stakeholders and Onyx leadership to develop a strategic roadmap for all customer-facing aspects of Onyx, including data assets, ontology, Knowledge Graph / semantic search, data / computing / analysis platforms, and data-powered applications.

We are seeking an experienced Product Manager II who will be accountable for designing and delivering the road map for molecule design products to support GSK Research and Development. This role will be pivotal in ensuring a cohesive enterprise level strategy towards molecule design solutions and will ensure our scientists have access to best-in-in-class technology products to improve research productivity and ultimately deliver new medicines for our patients. You will:

• Contribute to Product Development & Adoption:�Actively contribute to the full product lifecycle, from development to launch and adoption, focusing on specific features and components within novel molecule design solutions for the scientific community at GSK.

• Support GenAI Strategy:�Support the strategic integration and enhancement of GenAI capabilities within molecule design tools, helping to define and implement next-generation AI-powered functionalities.

• Collaborative Delivery:�Partner closely with Onyx tech teams, R&D scientists, and leaders to facilitate the delivery of impactful cloud-based products and solutions that leverage Generative AI and agentic capabilities.

In this role you will

• Product Strategy & Roadmap Contribution:�Contribute to the definition and execution of specific features and components within the molecule design solutions roadmap, ensuring alignment with the overall product strategy.

• User Research & Feedback Analysis:�Conduct user interviews, gather feedback, and analyze user data to inform the definition of product enhancements and identify opportunities for iterative improvements in molecule design tools.

• Product Feature Definition:�Work closely with Senior Product Managers and engineering teams to translate user needs into clear, well-defined product requirements, user stories, and acceptance criteria for discrete features.

• Agile Development Engagement:�Actively participate in agile ceremonies (e.g., sprint planning, backlog refinement, stand-ups) with engineering teams, ensuring product requirements are understood and supporting effective backlog management.

• GenAI Feature Implementation Support:

  • Contribute to the development and implementation of specific features within AI Agents, leveraging LLMs and Generative AI to automate well-defined parts of scientific research tasks.

  • Assist in the design and testing of human-agent interaction components, focusing on specific conversational flows or user interface elements to enhance usability.

  • Support the product lifecycle for individual models or agents by assisting with data gathering, testing of fine-tuned models, and developing documentation for APIs/agents.

  • Support the implementation of Model-In-The-Loop designs by gathering R&D user feedback and contributing to the

• Participate and contribute in highly technical product discussions with engineering leaders, translating ambiguous scientific objectives into precise requirements for fine-tuning foundational models, vector databases, and multi-agent system architectures.

• Cross-Functional Coordination: Coordinate with both tech and RD teams, including DevOps& Infrastructure, data engineering, computing platform engineering, data & knowledge platform engineering, program management teams and RD data leadership teams, to align product strategies, gather input, ensuring clear communication and smooth execution.

• Product Release Support:�Assist with product launch activities for new features, including preparing documentation, training materials, and support resources to ensure successful adoption.

• Performance Monitoring & Optimization:�Monitor key metrics for specific product features, gather user feedback on performance, and identify potential areas for improvement.

Why you?

Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:�

• Bachelors degree in Bioinformatics, Computational Biology, cheminformatics, AI/ML, Computer Science, Software Engineering, or related discipline.

• Experience in product management with a proven track record of shipping 0-to-1 software products powered by AI/GenAI, LLMs, or autonomous agents in a commercial or large-scale enterprise setting.

• Demonstrated experience executing product strategy for modern applications, including hands-on experience with technologies core to AI systems such as vector databases, MLOps, retrieval-augmented generation, and model fine-tuning.

• Demonstrated technical fluency with cloud-native architectures (e.g., AWS, GCP, Azure), API design, and the infrastructure required to serve and scale LLM-based applications.

Preferred Qualifications & Skills:

If you have the following characteristics, it would be a plus:

• Master�s degree or PhD in Bioinformatics, Computational Biology, Computational Chemistry, Data Science, Computer Science/Software Engineering, or related discipline Engineering, Cloud Computing or related discipline.

• Experience contributing to products that involve AI agents, their tool utilization (APIs, function calling), or the development of conversational AI interfaces.

• Hands-on software engineering or data science experience in an AI/GenAI-focused team prior to transitioning into product management.

• Familiarity with the architecture of modern transformer-based models and an understanding of the strategic trade-offs when selecting between proprietary, open-source, or fine-tuned custom models.

• Experience contributing to products that manage or interpret complex, unstructured biomedical data.

• Familiarity with Model Context Protocols (MCP) for LLM-powered agents, including basic concepts of prompt engineering, context window management, and maintaining model coherence in multi-turn interactions.

• Foundational knowledge of bioinformatics, computational biology, or cheminformatics, and an interest in how agentic AI can impact drug discovery.

• Hands-on experience with product management tools such as Confluence, Jira, Miro, Monday, Notion, etc.

• Previous experience in the life science industry or biopharma R&D is a plus.

Closing Date for Applications: Tuesday 6th January 2026 (COB)

Please note: As we approach the holiday season, our recruitment team and hiring managers will have limited availability between now and early January. We encourage you to apply and will review all applications, however response times may be longer than usual, and interviews may be scheduled after the New Year. We appreciate your understanding and look forward to connecting soon!

Please take a copy of the Job Description, as this will not be available post closure of the advert.�
When applying for this role, please use the �cover letter� of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application, you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. �If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.

#LI-GSK

#GSKOnyx

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391.� The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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This role within Global Clinical Oncology R&D will serve as a clinical sciences leader on global oncology studies and contribute to program-level activities. Responsible for the delivery of quality study strategy and design, understanding the analysis and interpretation of data throughout the study, including leading clinical data review ongoing throughout study conduct. Responsible for the end to end of writing protocols (protocol concept to final study report) delivery. Contributor to informed consent forms development and other study related documents.

Key Responsibilities:

• Review and/or enhance the technical and scientific robustness of project level clinical development plans.

• May support regulatory interactions, including contributing to briefing documents, presentations, addressing questions and responses.

• Ensure compliance with ICH/GCP guidelines, all applicable laws and regulations, and GSK SOPs, for all products and services delivered for their designated studies.

• Contribute to development of end-to-end clinical development strategy.

• Make decisions which balance risk/benefit with clear understanding of impact on the study and project; takes action to mitigate risk where appropriate.

• Actively partner to build relationships and collaborate with oncology aligned staff in other global functions.

• Responsible for cultivating strong relationships and robust communication among the clinical study/project team and GSK�s Oncology Clinical Development Organization. This includes training, education, onboarding as well as problem solving in the conduct of clinical trials.

• Encourage others within matrix and line teams to seek alternative perspectives and develop solutions.

• Study design and interpretation of study results that provide data to adequately address questions concerning efficacy/effectiveness, safety, applicability to targeted patient population, and clinical and commercial value that are consistent with the compounds� phase of development while ensuring that patient safety is of paramount concern and that regulatory requirements are incorporated through:

• Accountability for Study Team members/stakeholders, as appropriate and regulatory reporting at the study level by providing leadership at study level to assure overall safety of the study subjects.

• Drive/Contributing to clinical components of the IB, and documents for regulatory submissions and advisory requirement, including scientific advice, IND, EoP2, preNDA/BLA meetings, NDA/BLA and MAA documents.

• Serves as a product, protocol and project subject matter expert to support internal and external customers.

• Work with external experts to develop abstracts, manuscripts and study design presentations.

Basic Qualifications:

• Bachelor�s degree in life sciences or related discipline.

• 3 + years' experience in a pharmaceutical industry or CRO environment in the clinical development process.

• Oncology clinical development experience, particularly in the area of immuno-oncology.

• In depth knowledge of study management, global regulatory guidelines and ICH/GCP.

• Experience in developing and writing study protocols, study procedures manuals, informed consent forms and clinical study reports

• Experience working with investigators, site staff, external experts, Contract Research Organizations and vendors.

Preferred Qualifications:

• Advanced degree (e.g. MS, PhD, PharmD).

• Clinical development experience across all phases of development (I-IV).

• Excellent leadership skills.

• Highly developed communication skills appropriate to the target audience, promoting effective decision-making where necessary.

• Proven expertise in the proactive identification of issues which may impact clinical programs coupled with the ability to contribute to solutions affecting cross-functional matrix teams.

• Excellent influencing and negotiation skills

Why GSK?

Our values and expectations are at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: �

• Operating at pace and agile decision-making � using evidence and applying judgement to balance pace, rigour and risk.

• Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.

• Continuously looking for opportunities to learn, build skills and share learning.

• Sustaining energy and well-being

• Building strong relationships and collaboration, honest and open conversations.

• Budgeting and cost-consciousness

*LI-GSK

Please visit� GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

The Clinical Development Director- Renal, provides clinical and scientific insights and leadership to clinical and translational studies or programs within the Early Pipeline Unit (EPU) of the Respiratory, Immunology and Inflammation Research Unit (RIIRU). The appointed individual will work within project teams to plan, execute, and deliver activities including renal translational and clinical development strategies and clinical studies.� You will work cross-functionally to develop and execute clinical development plan(s) up to, and including, Proof of mechanism/Proof of concept studies.

This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following:

Key Accountabilities / Responsibilities:

• Support alignment of translational and clinical plans and study designs with project strategies to ensure quality execution of IEP and CDP. Will develop sections of core regulatory documents
• Generate the data and evidence required to determine a target or medicines� potential efficacy, safety profile, key areas of product differentiation and route to becoming a medicine with value to patients in the shortest possible timeframe
• Define and deliver the clinical pillars of the translational table. Deliver clinical development and study timelines and endpoints, including pharmacology, mechanism and clinical efficacy endpoints, enabling key decision points and Go/No Go criteria for the CDP.
• Seek and maintain relationships with program counterparts in Biology, Translational, Commercial, Research, Regulatory, Clinical Operations, Access, Medical Affairs and Statistics.
• Contribute to the implementation and embedding of strategic initiatives and various organizational initiatives in Clinical Development

Clinical Development Strategy; Study & Program Design:

• Provides effective support and oversight of R&D evidence generation activities to assure patient safety and study delivery.
• Contributes to the study team discussions on indication planning, incorporates input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc) to contribute to vital deliverables including early Medicine Profile, Target Validation, Translational Plans, Candidate Selection.
• Designs clinical development plans and study protocols across all phases of development, reflecting internal and external stakeholder input (e.g. patients, evidence generation, regulators, payors, pharmacovigilance)
• Develops clinical study protocols, amendments, investigator brochures, clinical study reports etc.
• Inputs to regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.
• Provides medical monitoring and oversight of the safety of study participants on behalf of the Sponsor during the study, together with Pharmacovigilance Physician. If physician, accountability for Medical Governance across the project to ensure scientific integrity and overall safety of the study subjects across the study.

Clinical Leadership:

• Accountable for leading the CMT on an EPU program.� Serves as a clinical point of contact both internally and externally for an indication of an asset indication (i.e. Pre-POC and single indication) or for a clinical study. Represents the clinical matrix team at EDT or clinical study at CMT.
• Collaborate with cross-functional teams, including biology, translational, regulatory affairs, medical affairs, and commercial teams, to ensure cohesive and comprehensive translational and clinical development plans. Act as Clinical Lead at study level.
• Actively leads the end-to-end clinical development strategy for an EPU program and may contribute to later stages.� Serve as the primary point of contact for an investigational agent (early development) or clinical study for internal and external stakeholders, including regulatory agencies, key opinion leaders, and clinical investigators.
• Serves as the primary clinical interface with the relevant internal RIIRU/GSK review board (ie Technical Review or governance) and/or Protocol Review Board.
• Clinical evaluation of business development opportunities.
• Stays abreast of advancements in renal research, clinical trial methodologies, competitive environment and regulatory space to maintain GSK�s competitive edge. Identifies and highlights transformational opportunity where projects can offer highly significant benefit to patients in ways not possible with existing approaches.
• Gathers and supports the integration of inputs from across disciplines (scientific, clinical commercial, regulatory) to contribute to clinical components of the Medicine Profile. Consistently contributes to solving study and overall clinical development plan problems.
• Contributes to the implementation and embedding of strategic initiatives and various organizational initiatives in the EPU.
• Demonstrates ability to influence others at project, departmental and inter-departmental levels, as appropriate

Influencing and inspiring others, managing conflict:

• Able to consistently inspire others by setting a positive example, communicating a compelling vision, and creating an environment where team members feel valued and motivated.
• Demonstrated experience in managing conflicts effectively and independently, negotiating mutually acceptable solutions.
• Consistently achieves desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support.

Enterprise mindset and navigating ambiguity:

• Demonstrated flexibility and adaptability in changing environments, able to analyze incomplete information, identify potential risks and implications, and make informed decisions
• Demonstrated enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.
• Embraces challenge as an opportunity for creativity and uses new learning and digital tools to create innovation in other areas
• Proactively generates ideas for innovative improvement and takes advantage of opportunities that arise; promotes environment for others to generate ideas for improvement

�Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• PhD or Pharm D (or equivalent) with 1-3 years postgrad experience in a relevant postgraduate training or job.
• Minimum of 3 years of experience in clinical research and development (may include postgrad experience)
• Robust knowledge of renal specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution.
• Experience working with global regulatory agencies and managing global clinical trials in nephrology.
• Knowledge of regulatory requirements, Good Clinical Practice (GCP), and ethical guidelines for clinical research.
• Demonstrated ability to work collaboratively in cross-functional teams and a matrix environment to design and execute trials to regulatory standards.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Medical Degree and Board certified/eligible in Nephrology
• Experience in contributing to NDA, BLA, or MAA submissions preferred

Why GSK?

Our values and expectations�are at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391.� The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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Executive Medical Director / SERM Head - Oncology

We are seeking a visionary and strategic leader to join our Global Safety Evaluation and Risk Management team as SERM Head, Executive Director. This is a critical leadership role responsible for shaping and driving the clinical safety and pharmacovigilance strategy across our Oncology portfolio, ensuring the highest standards of patient safety and regulatory compliance.

Key Responsibilities

• Lead and inspire a global team of senior medical and scientific safety professionals.
• Define and drive the strategic direction and vision of clinical safety and pharmacovigilance activities in alignment with Global Safety business strategy.
• Oversee benefit-risk management activities across the assigned portfolio throughout the lifecycle, to ensure Patient Safety globally. Anticipate, detect and address product safety issues and ensure that risk-reduction strategies are implemented appropriately.
• Ensure scientific rigor in safety data evaluation, interpretation, and communication. Make recommendations for the further characterization, management, and communication of safety risks
• Represent Global Safety with confidence, impact, integrity and professionalism both internally, in cross-functional governance, and with key external stakeholders including regulators and industry forums.
• Drive continuous improvement and compliance with applicable processes and standards and maintain readiness in internal audit or regulatory inspection.
• Lead or oversee SERM contribution to due diligence activities.
• Lead enterprise-wide activities such as safety advisory panels, interfaces with and assumes ad hoc membership of a Senior Governance Committee.

Required Qualifications

• Medical degree and a clinical medical specialty qualification
• Extensive experience in clinical safety, pharmacovigilance, or drug development within the pharmaceutical or biotech industry.
• Demonstrated expertise in Oncology and/or Hematology therapeutic areas.
• Proven leadership in global safety strategy and team management.

Preferred Experience

• Deep understanding of regulatory requirements and benefit-risk methodologies.
• Exceptional communication and stakeholder engagement skills.
• Experience working in matrixed, global environments.
• Familiarity with both clinical development and post-marketing safety.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391.� The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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Director, Privacy R&D and CPO

Job Purpose

A Director Privacy for R&D/CPO ensures compliance with global data protection laws like GDPR and HIPAA. They mitigate privacy risks and safeguard sensitive health data to ensure patient privacy right are respected and right avoid legal and reputational damage. The role fosters study participants trust by ensuring confidentiality and ethical data handling in research. They oversee data governance, ensuring secure and appropriate use of information. The Director provides strategic guidance in product development, partnerships, and mergers, integrating privacy into innovation. They lead training initiatives to build a privacy-conscious organizational culture across R&D and CPO. The role enhances security and supports digital health initiatives. Ultimately, it protects both the company and patient interests in a highly regulated sector.

The role will also have line management responsibilities. The job holder will report to the Head of Bioethics and CMO Oversight.

Key Responsibilities

• Develop and implement a strategy to ensure Privacy by Design into R&D & CPO processes. This includes completing new or adjusting existing privacy inventories and/or privacy risk assessments and developing and implementing mitigating controls.
• Oversee the privacy strategy to ensure timely create and review existing R&D & CPO privacy inventories and privacy impact assessments to identify gaps, assign appropriate actions, and track actions to completion. �Ensure new innovative areas are timely addressed and risk identified including adequate review of third-party global process relevant to the enterprise risk.
• Provide inventory and monitor R&D/CPO privacy gaps, risks and issues as well as developing adequate risk minimization measures, corrective and preventative actions.� Provide status updates to senior governance bodies such as R&D�s Risk Management and Compliance Board (RDCB) and Data Ethic and Governance Council as well as CPO related board.
• Support the design of privacy-related training for R&D & CPO staff to foster a privacy by design culture.
• Analyze and implement process changes required to enhance R&D/CPO Privacy framework.
• Maintain ongoing communication with relevant LOC stakeholders, Privacy Legal, Data Privacy Officer and enterprise risk ensuring continued alignment between global and local R&D/CPO Privacy processes.
• Coordinate efforts with the privacy lead needed to respond to Data Privacy Regulators in the event of Data Privacy Breaches. Monitor frequency and resolution of breach as well as implement remediation strategy to avoid recurrence. Coordinate with privacy lead responses to Individual Rights Management requests, ensuring engagement of the right R&D stakeholders in the information collection.
• Oversee and ensure adequate privacy expertise related to the data and human biological sample reuse (including adequate support to the DSAP panel).
• Create and maintain R&D/CPO�s approach to the GSK Privacy Enterprise Risk Plan and maintain ongoing communication with Privacy professionals in other GSK business areas as well as maintain the R&D/CPO privacy champion network.
• Provide Risk Management expertise and oversight for R&D/CPO Privacy covering all therapy areas and with global-regional-local span.�
• Cocreate with GSK Enterprise Risk Owner, R&D Enterprise Risk owner, and R&D Enterprise Risk Coordinator, and Risk Council Business members to define R&D�s risk strategy, appetite, the nature and scope of risk, and the approach to embed, assess and enhance the internal control framework maturity which encompasses Risk Management, Management Monitoring, Control Document(s), Training and Independent Business Monitoring.
• Lead the review of R&D/CPO risks and updates the Risk Register with the privacy leaders and, performs risk assessments related to control deficiencies, root cause analysis, after action reviews, process detailed reviews, etc.
• Ensure a sustainable, controlled, R&D/CPO enterprise risk management plan is in place and that decision making is applied in a consistent manner across similar issues. Ensure a mechanism of lessons learned is in place to share with privacy leads and community of parctise as appropriate stakeholders within the organization.
• Escalate any relevant risks to appropriate bodies within the organization - R&D RDCB (R&D Risk Management Compliance Board) and GSK boards (ROCC, ARC, CRC, Science Committee). Oversee the escalation process.
• Maintain up to date and in-depth knowledge of appropriate national and international regulatory legislation and guidelines; and the impact to business area processes and procedures. Additionally, ensure intelligence is utilized for continuous improvement of Internal Control Framework of business processes relevant to the enterprise risk.
• Educate, guide and influence GSK management and staff on best quality and compliance policy and practices, especially as they relate to areas of identified responsibility.
• Support the development, management, and implementation of processes, associated written standards and job aides specific to Privacy to support effective management of Regulatory Inspections and Issue Investigations across GSK R&D/CPO.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• Expertise in essential regulation guidelines and medical governance policies and procedures applicable to R&D.
• Broad scientific/ pharmaceutical industry background with more than 10 years of experience in privacy EU and ex EU.
• Previous experience in implementing / embedding Privacy risk controls into a worldwide organization
• Proven success in developing and executing activities that improve the application of the internal control framework
• Good understanding of privacy regulatory framework
• Relevant experience in governance type activities with understanding of the R&D, medical, commercial and compliance functions.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Accreditation/qualification in Privacy
• Strong Bioethical mindset, and ability to evaluate complex cases.� Able to substantial and leverage various bioethical options in autonomy.
• Ability to incorporate strategy & organizational considerations and to operationalize them.
• Performance and results driven with Proven sense of urgency.
• Possesses excellent English language written and verbal communication skills in addition to proven negotiation skills.
• Excellent communication and presentations skills, ability to facilitate interfaces within an extended network including Senior Leaders and external experts, proven experience in negotiating and influencing at different levels of the organization.
• Ability to resolve problems with use of knowledge, information and networks in a flexible way and to be successful in a matrix environment.
• Self-motivated with the ability to work independently, to develop credibility with colleagues within and outside GSK.
• Act as a role model in line with GSK core values and behaviours.
• Comfortable to evolve in changing and challenging environment.
• Ability to set directions, lead and motivate a team to deliver in a changing and challenging environment. Mentoring and coaching of staff to manage performance, motivation, talent and knowledge building.
• Risk management or business experience with Privacy

?

If you have a disability and require assistance during the course of the selection process, you will have the opportunity to let us know what specific assistance you require in order to make suitable arrangements.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

As an Associate Director, Content Approval for Vaccines, you will play a pivotal role in ensuring the global promotional and non-promotional content meets the highest standards of quality, scientific accuracy, balance, and compliance. This includes adherence to internal GSK standards and applicable external regulations, including a robust understanding of the ABPI code of practice. This role will involve the fostering of robust relationships and collaborations within a highly matrixed environment which includes but is not limited to Commercial, Legal, Medical Affairs, Regulatory Affairs, Clinical Development, and third-party suppliers at a Global level.

Key Responsibilities:

This role will provide you the opportunity to utilize your expertise in the scientific area, understanding of the internal business strategies, applicable GSK processes/policies, and the external regulations including the ABPI code of practice to ensure global content is compliant, accurate, up-to-date, and fit for purpose for external engagement.� These responsibilities include the following:

• Primary medical reviewer and/or approver who is accountable for the thorough, timely review and approval of Global promotional and non-promotional materials.

• Ensure content is scientifically accurate, meets the scientific rigor (i.e., levels of evidence); is fair-balanced and meets the GSK requirements/standards/processes as well as complies with applicable external regulations (incl. ABPI Code where relevant)

• Maintain deep scientific and therapeutic expertise on assigned products and therapy areas

• Maintain a deep understanding of ABPI Code of practice (as an AQP/Appropriately Qualified Person) and the GSK interpretation/position to ensure consistent application while reviewing and/or approving global medical or commercial content in scope of ABPI.

• Strong understanding of the business strategies/unmet needs to ensure the content is aligned with current medical practices/guidelines, and the content is fit for purpose to the targeted audience.�

• Work alongside MI counterparts and various business partners to align, validate, and identify solutions to ensure content is of the highest quality and relevant to the audience

• Provide timely feedback and recommendations for content created and/or reviewed by third-party vendors and escalate when third-party vendors do not meet the quality standards

• Address and/or escalate to appropriate leadership when content may result in a risk to the business

• Stay up to date with evolving regulatory requirements, industry standards, and best practices to ensure continuous compliance

• Identify issues, themes and/or opportunities for continuous improvement that enhance the quality and compliance of materials and activities

• Serve as a key point of contact for regulatory and legal teams during audits and inspections, providing documentation and insights as needed

• Actively participate in workstreams to develop best practices, ways of working and continuous improvement for promotional and non-promotional content approval process

• Actively contribute and provide input to content creation plans to ensure content deliverables and timelines are realistic and achievable

• Support other GMI&CA team activities (e.g. MI content creation, US medical review), when required and in onboarding new content approval team members.

Why You?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• Master�s/Graduate Degree in Life Sciences or Healthcare

• 4+ years of pharmaceutical industry experience�

• 3+ years of Medical Affairs experience�as a reviewer of content used in promotional and non-promotional settings

• Experience with commercial and medical activities from a global perspective in the pharmaceutical industry (e.g., promotion, medical education, external partnerships, advisory boards)

• Experience with evaluation of clinical literature

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Strong understanding of content approval requirements incl. external regulations (e.g. ABPI Code)�

• Strong understanding of international Codes of Practice FDA, IFPMA, EFIPIA, IPHA, ABPI etc.

• Capable to cope with pressure and meet tight timelines

• Experience of working at both global and local country level�

• Experience working with global teams in a matrix environment

• Ability to work effectively with others, delegate appropriately and foster a strong culture of teamwork

• Experience in Vaccines

• Strong organizational and planning skills�

• Strong communication and collaboration skills

• Ability to work independently and manage/prioritize multiple projects simultaneously

• Ability to accurately evaluate and summarize complex scientific literature, real-world evidence, and other observational research studies for scientific evaluation needs by various customer types

• Ability to clearly communicate complex scientific data in a concise and accurate manner

• Demonstrated customer-focus, problem solving abilities and strong conflict resolution skills

Please visit� GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

The VP, Analytical Science & Technology, is accountable for leading the global Analytical Science and Technology organization in MSAT, Global Supply Chain (GSC), to provide enterprise-wide (biopharma, small molecule, vaccine) analytical support and to integrate specialist analytical science capabilities that support quality control (QC), deeper characterization, and comparability. In addition, the role is accountable for driving innovation and modernization of analytical capabilities, industrializing new analytical technologies, implementing platform analyses and automation into modern QC, and establishing an updated regulatory framework for new product introductions (NPIs) and existing commercial projects in GSC.

This role manages the integration and translation of analytical and materials science outputs from R&D into GSC. It ensures late?phase NPI assets have robust analytical and materials strategies that meet product lifecycle needs, and uses these insights to shape the strategic direction of R&D. It is also accountable for setting the strategic direction and developing analytical and materials science capability across the GSC network, and for overseeing the global rollout and implementation of business?critical standards, including method and specification alignment, comparability protocol best practices, and the material risk assessment process across GSC.

Finally, the VP ensures the generation of critical data to support control strategies and to ensure quality, safe medicines reach all our patients, and delivers excellence in quality analytical methods, data, and knowledge to enable key decisions during technology transfer to commercial manufacturing and to ensure supply of all critical products.

The global Analytical Science & Technology function comprises a global team of multi-disciplinary Analytical Science & Technology Leads (ASTLs), MSAT characterization hub leads, and scientists at different sites, whose core responsibilities include:

�� Provide global technical leadership for analytical method transfer, development and optimization, qualification, validation, troubleshooting and investigation, including evaluation of impacts on product stability, control and specification strategy.

�� Deliver decision-making guidance and direct testing support for biophysical, biochemical, biological, immunochemical and immunological characterizations, reflecting the complexity and intrinsic heterogeneity of monoclonal antibodies and antibody-related products, and provide the technologies and criteria used to characterize them.

�� Provide strategic decision-making and direct testing for physical properties testing, spectroscopy, imaging, surface analysis and materials science characterization of established and new small-molecule portfolios.

�� Develop analytical methods for critical quality attributes and product characterization and provide strategic guidance across-product for critical quality attribute assessment, control strategy, specification setting and comparability criteria.

�� Present strategic recommendations across the analytical network and ensure the team of ASTLs serve as key scientific and technical representatives on cross-functional teams (CMC, Regulatory, Quality, Manufacturing, R&D, etc.).

�� Develop analytical testing plans for internal laboratories or for contract manufacturing organisations (CMOs) and provide technical oversight for outsourced testing.

�� Build strong connections to the GSK Global Supply Chain regulatory and technical agenda and business interests by ensuring operational excellence while introducing new ways of working and interactions through the MSAT hubs and all supporting organisations.

�� Develop comprehensive product characterization packages to support regulatory filings and actively support GSK Global Supply Chain positions with EU, US and other regulatory authorities as technical expert leaders.

Key Responsibilities in Detail

�� Lead and deliver complex, business-critical projects across multiple supply chains and sites, requiring the ability to lead in an environment with a high degree of change and uncertainty.

�� Lead and develop a large, high-performing team of multi-disciplinary Manufacturing Science and Technology (MSAT) team of subject-matter experts to deliver business-critical projects (more than 100 per year) with continuously changing priorities and deadlines, to avoid significant supply and patient risks.

�� Serve as a core member of the MSAT Leadership team, responsible for setting strategy and directing training the global Analytical Science & Technology organization, and for ensuring capability across sustainable biopharma, small molecule, and vaccine pipelines in the GSC network.

�� Be accountable for the global rollout and implementation of business-critical standards, including method and specification alignment, comparability protocol best practice, and the material risk assessment process across GSC.

�� Be accountable for ensuring late-phase NPI assets have an analytical and materials science strategy to underpin their product lifecycle requirements, and for influencing the strategic direction of R&D in these sciences.

�� Assure the safety of staff and provide risk oversight for the global Analytical Science & Technology team spanning EU, US and East Asia.

�� Be accountable for the definition and implementation of the analytical strategy in MSAT, including modernization, and for delivering agreed functional performance, efficiency plans, targets and savings to meet GSC priorities.

�� Provide technical input into governance boards (Specification Board, Tech Council, Comparability SSO) and influence and support other MSAT heads, R&D leads and senior stakeholders on R&D boards such as the CMC Board.

�� Create an environment that embraces inclusion to deliver a modern, dynamic working environment across the function, with tiered accountabilities between Analytical Science & Technology Leads, characterization hub leads, and scientists to grow an engaged team.

�� Ensure alignment with R&D, commercial manufacturing and external partners to enable effective and efficient delivery of the small- and large-molecule portfolios. This includes providing an aligned analytical-QC view for CMC partners, ensuring a well-integrated �one analytical CMC team�, and maintaining a seamless interface between R&D, analytical MSAT and QC; commercial supply chain, logistics and manufacturing sites; therapeutic area and franchise groups; and local operating companies and external partners.
�

Basic Qualifications:

• Master�s degree in a relevant science or engineering discipline, or equivalent industry experience.
• Experience leading significantly sized departments or functions, with leading leaders and delivering strategic scientific leadership in a pharma/biotech organization
• 15+ years� experience with a PhD, or 18+ years with an MS, or 20+ years with a BS in a scientific discipline (e.g. biochemistry, biology or a related field), including 7-10+ years� experience in analytical development and/or testing.
• Experience with analytical methods, current cGMP and US/EU/ROW regulatory requirements, and statistical data analysis.
• Experience in assay development and qualification.
• Experience in regulatory document writing, review and audits.
• Experience across primary and secondary manufacturing and across small and large molecule domains.
• Experience influencing across supply chains and manufacturing sites, procurement, strategy and R&D.
• Experience managing global direct and matrix teams.
• Experience developing leaders at director level and above.
• Experience analysing trend and metrics data (especially related to quality, safety, technical requirements and performance) to drive continuous improvement.
• Experience effectively handling and appropriately escalating issues based on risk in a timely manner.
  �

Preferred Qualifications and experience:

• PhD in a relevant science or engineering discipline preferred.
• Consistently acts and leads with personal accountability for the quality and compliance of the MSAT team and the broader organisation.
• Excellent management, communication and interpersonal skills, with the ability to set ambitious goals, drive results, define priorities, and manage and influence individual and team performance; proven ability to organise people and activities to achieve objectives.
• Ability to communicate effectively (written and verbal) and influence key stakeholders at all levels of the organisation, both internally and externally.
• Expansive, visionary thinker with the ability to drive strategic partnerships and long-term scientific strategy.
• Strong technical and business acumen.
• Proven relationship builder with negotiation skills.
• Thrives in a fast-paced environment with potential for significant change and remains calm and effective under pressure and in conflict.
• Deep understanding of the complexity and interdependencies of development activities required to deliver a commercial manufacturing process, including characterization and comparability needs.
• Strong appreciation of the key risks and failure modes across development and the commercial supply chain, with the ability to discuss and monitor these risks effectively.

How to apply

If this role motivates you, we encourage you to apply. Tell us how your experience and approach match the responsibilities and qualifications above. We welcome applicants from all backgrounds and promote inclusion, collaboration, and a supportive environment where people can grow and succeed.

#LI-GSK

Closing date for applications: 19th December 2025

Please visit� GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK�s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Sterile Value Stream Director Barnard Castle

The posting period will end on the 15th of December in 2025

Job purpose:

As Sterile Value Stream Director, you will be accountable for leading end-to-end sterile operations across the Barnard Castle value stream. You will define and deliver the strategic transformation required to move the site from foundational rebuild to scale and excellence, ensuring safe, compliant, and cost-effective supply of sterile medicines to global markets. This is a visible, high impact, site based full time leadership role that requires experience in sterile manufacturing, strategic thinking, and proven capability to lead large scale change across people, processes, and technology.

A key element of the role is to create and sustain high performing management teams and to develop managers across the site who can embed and sustain operational excellence. The role covers a diverse range of product modalities including small and medium molecules, large molecules, monoclonal antibodies (mAbs), oligonucleotides and other advanced modalities.

Key responsibilities:

• Strategic Leadership: Define and execute the sterile value stream strategy to deliver Barnard Castle�s vision for transformation, growth, and excellence. Translate global strategy into pragmatic, measurable site level plans
• Unify Manufacturing Teams: Break down silos and build a single, integrated one team manufacturing organisation across sterile operations, fostering alignment, shared accountability, and consistent execution across all manufacturing leaders
• Create High Performing Management Teams: Build, coach, and hold accountable a strong leadership team capable of delivering site objectives. Establish clear leadership structures, roles, and decision rights; set expectations and development plans; and ensure leaders model desired behaviours and drive performance
• Develop Leaders and Succession Plans: Implement leadership development programmes, mentorship and coaching frameworks, and succession planning to ensure bench strength and continuity. Promote a culture of compliance, continuous learning and leadership capability building at all levels
• Drive Change and Transformation: Lead change management programmes to rebuild foundational systems, embed new ways of working, and accelerate performance improvement. Sponsor and sustain lean/CI initiatives across sterile operations
• Digitalisation and AI Strategy: Shape and lead adoption of digital and AI enabled solutions to improve data driven decision making, predictive maintenance, process control, and workforce capability for future ready manufacturing
• Operational Delivery & Process Optimization: Oversee end to end sterile value stream processes including aseptic and terminal sterilisation, robotic filling, nano milling, and cold chain processing. Champion and drive productivity, yield, and throughput improvements using advanced technologies, ensuring approaches are appropriate to each modality (e.g., mAbs and oligonucleotides require specific cold chain, material handling and contamination control strategies)
• Quality, Compliance & Safety Accountability: Take ownership for product quality and regulatory compliance across sterile operations. Embed a safety-first culture and ensure robust systems and behaviours that meet GSK and global regulatory standards, including modality specific regulatory expectations for biologics, mAbs and oligonucleotides
• Performance Monitoring: Define and track KPIs across people, safety, efficiency, quality, cost, and delivery. Use data and insights to drive corrective actions, continuous improvement, and measurable outcomes
• Resource Allocation & Financial Stewardship: Prioritise and optimise allocation of materials, people, and equipment to meet production goals while controlling operational cost and capital investments
• Technology Optimization: Maximise value from technologies such as robotic filling, single use systems, HVLD and vacuum decay leak detection, inspection automation, RABS/CIP SIP systems, nano milling, and integrated eBRS systems. Ensure technology choices and validation strategies meet the needs of mAb and oligonucleotide manufacture where applicable
• Foundational Shifts & Integration: Lead the rebuild of core processes and systems and ensure seamless integration with GSK�s global network � sharing best practice and aligning sterile manufacturing standards
• Stakeholder Collaboration: Partner with functional leaders � Quality, Regulatory, Engineering, Supply Chain, MSAT, Finance, and EHS � and with external suppliers and regulators to align strategy and delivery
• Talent & Culture: Build leadership capability, succession plans, and a high-performance team culture. Mentor and develop people to sustain long term operational excellence. Drive inclusion, empowerment and accountability across teams
• Capital & Investment: Accountability for the leadership, introduction of operational investments of new technologies, lines, equipment�s and capabilities

Technologies & Capabilities You�ll Work With

• Aseptic Filling: Robotic filling under VHP isolators (e.g., QF01), single use technology, peristaltic pumps, vacuum stoppering, syringe and vial lines
• Terminal Sterilisation: RABS filling lines, CIP/SIP systems, autoclaves and associated terminal sterilisation processes
• Inspection & Leak Detection: Automated visual inspection (Brevetti, Innoscan, Eisai), HVLD (Bosch), vacuum decay (Wilcomat), manual inspection
• Packaging & Assembly: Automated device assembly for syringes (Ypsomate, SSD, Molly), labelling, tray sealing, carton and case packaging systems
• Nano Milling & Cold Chain: Suspension nano milling (50L), cold chain small batch processing for high value biologics, specialised temperature controlled logistics and handling for mAbs and oligonucleotides
• Biologics Specific Considerations: Viral clearance/PRT strategy awareness for mAbs, stringent contamination control and hold time management, analytics and stability support appropriate for biologic modalities
• IT/Automation: Integrated IT and automation platforms including electronic Batch Records (eBRS), process control and analytics systems

Products Manufactured at the Site

• Large molecules: treatments for autoimmune diseases, severe asthma, oncology
• Monoclonal antibodies (mAbs): large molecule biologics targeting oncology, autoimmune and other indications
• Oligonucleotides: advanced modalities including siRNA, antisense oligonucleotides and related chemistries
• Small molecules: treatments for migraine, influenza, HIV/AIDS, HIV prevention
• Medium molecules: treatments such as for pulmonary arterial hypertension
• Other advanced modalities are also handled at the site

Qualifications & Experience

• Academic: Bachelor�s degree in Business, Engineering, Operations, Supply Chain, Quality Management, or related field. Relevant professional certifications (Lean Six Sigma, PMP) highly desirable
• Experience: in sterile pharmaceutical manufacturing, including aseptic processing and terminal sterilisation; substantial experience leading large scale sterile operations and transformation programmes
• Leadership: Demonstrated ability to unify cross functional manufacturing teams, build high performing leadership teams, and drive change across complex organisations
• Leader Development: Proven experience designing and delivering leadership development, transformational change, succession planning, coaching and talent management programmes that uplift site capability and performance
• Technical Expertise: In depth knowledge of aseptic filling technologies, RABS/VHP processes, HVLD and vacuum decay leak detection, single use systems, and nano milling. Experience with eBRS and integrated automation preferred. Practical experience with biologics, including mAbs and oligonucleotide handling and associated process controls highly desirable
• Digital & AI: Proven track record implementing digitalisation and AI driven improvements within manufacturing environments
• Regulatory & Quality Accountability: Strong track record of driving compliance, regulatory readiness, and quality excellence across modalities including biologics
• Continuous Improvement: Demonstrated success applying lean methodologies and CI tools to deliver measurable operational improvements
• Interpersonal Skills: Exceptional strategic thinking, stakeholder management, communication, and people development skills
• Global Partnership: Experience collaborating with global strategy teams and aligning site level plans with network level objectives

Why this Role Matters?

This is a transformational and highly visible role with significant strategic impact on GSK�s ability to supply life saving sterile medicines worldwide. The Sterile Value Stream Director will directly influence patient safety, product quality, and the long term competitiveness of Barnard Castle through bold leadership, technical expertise, and a relentless focus on change and continuous improvement. By creating and developing high performing leadership teams and leaders across the site, the role will ensure sustainable delivery of excellence and resilience into the future, enabling safe, compliant, and scalable manufacture of small molecules, medium molecules, large molecules, monoclonal antibodies and advanced modalities such as oligonucleotides

*LI-GSK

Sterile Value Stream Director Barnard Castle

The posting period will end on the 15th of December in 2025

Job purpose:

As Sterile Value Stream Director, you will be accountable for leading end-to-end sterile operations across the Barnard Castle value stream. You will define and deliver the strategic transformation required to move the site from foundational rebuild to scale and excellence, ensuring safe, compliant, and cost-effective supply of sterile medicines to global markets. This is a visible, high impact, site based full time leadership role that requires experience in sterile manufacturing, strategic thinking, and proven capability to lead large scale change across people, processes, and technology.

A key element of the role is to create and sustain high performing management teams and to develop managers across the site who can embed and sustain operational excellence. The role covers a diverse range of product modalities including small and medium molecules, large molecules, monoclonal antibodies (mAbs), oligonucleotides and other advanced modalities.

Key responsibilities:

• Strategic Leadership: Define and execute the sterile value stream strategy to deliver Barnard Castle�s vision for transformation, growth, and excellence. Translate global strategy into pragmatic, measurable site level plans
• Unify Manufacturing Teams: Break down silos and build a single, integrated one team manufacturing organisation across sterile operations, fostering alignment, shared accountability, and consistent execution across all manufacturing leaders
• Create High Performing Management Teams: Build, coach, and hold accountable a strong leadership team capable of delivering site objectives. Establish clear leadership structures, roles, and decision rights; set expectations and development plans; and ensure leaders model desired behaviours and drive performance
• Develop Leaders and Succession Plans: Implement leadership development programmes, mentorship and coaching frameworks, and succession planning to ensure bench strength and continuity. Promote a culture of compliance, continuous learning and leadership capability building at all levels
• Drive Change and Transformation: Lead change management programmes to rebuild foundational systems, embed new ways of working, and accelerate performance improvement. Sponsor and sustain lean/CI initiatives across sterile operations
• Digitalisation and AI Strategy: Shape and lead adoption of digital and AI enabled solutions to improve data driven decision making, predictive maintenance, process control, and workforce capability for future ready manufacturing
• Operational Delivery & Process Optimization: Oversee end to end sterile value stream processes including aseptic and terminal sterilisation, robotic filling, nano milling, and cold chain processing. Champion and drive productivity, yield, and throughput improvements using advanced technologies, ensuring approaches are appropriate to each modality (e.g., mAbs and oligonucleotides require specific cold chain, material handling and contamination control strategies)
• Quality, Compliance & Safety Accountability: Take ownership for product quality and regulatory compliance across sterile operations. Embed a safety-first culture and ensure robust systems and behaviours that meet GSK and global regulatory standards, including modality specific regulatory expectations for biologics, mAbs and oligonucleotides
• Performance Monitoring: Define and track KPIs across people, safety, efficiency, quality, cost, and delivery. Use data and insights to drive corrective actions, continuous improvement, and measurable outcomes
• Resource Allocation & Financial Stewardship: Prioritise and optimise allocation of materials, people, and equipment to meet production goals while controlling operational cost and capital investments
• Technology Optimization: Maximise value from technologies such as robotic filling, single use systems, HVLD and vacuum decay leak detection, inspection automation, RABS/CIP SIP systems, nano milling, and integrated eBRS systems. Ensure technology choices and validation strategies meet the needs of mAb and oligonucleotide manufacture where applicable
• Foundational Shifts & Integration: Lead the rebuild of core processes and systems and ensure seamless integration with GSK�s global network � sharing best practice and aligning sterile manufacturing standards
• Stakeholder Collaboration: Partner with functional leaders � Quality, Regulatory, Engineering, Supply Chain, MSAT, Finance, and EHS � and with external suppliers and regulators to align strategy and delivery
• Talent & Culture: Build leadership capability, succession plans, and a high-performance team culture. Mentor and develop people to sustain long term operational excellence. Drive inclusion, empowerment and accountability across teams
• Capital & Investment: Accountability for the leadership, introduction of operational investments of new technologies, lines, equipment�s and capabilities

Technologies & Capabilities You�ll Work With

• Aseptic Filling: Robotic filling under VHP isolators (e.g., QF01), single use technology, peristaltic pumps, vacuum stoppering, syringe and vial lines
• Terminal Sterilisation: RABS filling lines, CIP/SIP systems, autoclaves and associated terminal sterilisation processes
• Inspection & Leak Detection: Automated visual inspection (Brevetti, Innoscan, Eisai), HVLD (Bosch), vacuum decay (Wilcomat), manual inspection
• Packaging & Assembly: Automated device assembly for syringes (Ypsomate, SSD, Molly), labelling, tray sealing, carton and case packaging systems
• Nano Milling & Cold Chain: Suspension nano milling (50L), cold chain small batch processing for high value biologics, specialised temperature controlled logistics and handling for mAbs and oligonucleotides
• Biologics Specific Considerations: Viral clearance/PRT strategy awareness for mAbs, stringent contamination control and hold time management, analytics and stability support appropriate for biologic modalities
• IT/Automation: Integrated IT and automation platforms including electronic Batch Records (eBRS), process control and analytics systems

Products Manufactured at the Site

• Large molecules: treatments for autoimmune diseases, severe asthma, oncology
• Monoclonal antibodies (mAbs): large molecule biologics targeting oncology, autoimmune and other indications
• Oligonucleotides: advanced modalities including siRNA, antisense oligonucleotides and related chemistries
• Small molecules: treatments for migraine, influenza, HIV/AIDS, HIV prevention
• Medium molecules: treatments such as for pulmonary arterial hypertension
• Other advanced modalities are also handled at the site

Qualifications & Experience

• Academic: Bachelor�s degree in Business, Engineering, Operations, Supply Chain, Quality Management, or related field. Relevant professional certifications (Lean Six Sigma, PMP) highly desirable
• Experience: in sterile pharmaceutical manufacturing, including aseptic processing and terminal sterilisation; substantial experience leading large scale sterile operations and transformation programmes
• Leadership: Demonstrated ability to unify cross functional manufacturing teams, build high performing leadership teams, and drive change across complex organisations
• Leader Development: Proven experience designing and delivering leadership development, transformational change, succession planning, coaching and talent management programmes that uplift site capability and performance
• Technical Expertise: In depth knowledge of aseptic filling technologies, RABS/VHP processes, HVLD and vacuum decay leak detection, single use systems, and nano milling. Experience with eBRS and integrated automation preferred. Practical experience with biologics, including mAbs and oligonucleotide handling and associated process controls highly desirable
• Digital & AI: Proven track record implementing digitalisation and AI driven improvements within manufacturing environments
• Regulatory & Quality Accountability: Strong track record of driving compliance, regulatory readiness, and quality excellence across modalities including biologics
• Continuous Improvement: Demonstrated success applying lean methodologies and CI tools to deliver measurable operational improvements
• Interpersonal Skills: Exceptional strategic thinking, stakeholder management, communication, and people development skills
• Global Partnership: Experience collaborating with global strategy teams and aligning site level plans with network level objectives

Why this Role Matters?

This is a transformational and highly visible role with significant strategic impact on GSK�s ability to supply life saving sterile medicines worldwide. The Sterile Value Stream Director will directly influence patient safety, product quality, and the long term competitiveness of Barnard Castle through bold leadership, technical expertise, and a relentless focus on change and continuous improvement. By creating and developing high performing leadership teams and leaders across the site, the role will ensure sustainable delivery of excellence and resilience into the future, enabling safe, compliant, and scalable manufacture of small molecules, medium molecules, large molecules, monoclonal antibodies and advanced modalities such as oligonucleotides

*LI-GSK

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases � to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we�re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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