Do you have an entrepreneurial spirit, insatiable curiosity, broad pharma expertise, and a strong commitment to deploying insights to guide business strategy? If so, consider being a key partner in the growth of GSK Oncology as a Director, Global Strategic Insights (GSI), Oncology Early Pipeline.

GSK is seeking a collaborative, insight‑driven individual to help shape the Global Product Strategy within our Oncology organization. In this role, you will generate strategic insights that guide early pipeline decision‑making, inform business development opportunities, and support key above‑brand initiatives. Your contributions will play a critical part in strengthening the overall value and future potential of GSK’s Oncology pipeline. Working closely with the Head of GSI Oncology Early Pipeline, you will:

• Be a thought-partner to early product strategy leads.
• Partner with the Global Competitive Intelligence team to closely monitor the latest external developments and translate these into concise and impactful recommendations with cross-functional input.
• Lead on insight generation to shape and drive commercial forecasts for early pipeline and business development governance milestones; in close partnership with cross-functional teams.
• Partner cross-functionally on business development search and evaluation initiatives
• Leverage technology and innovation to accelerate senior leader decision-making.
• Generate actionable and concise recommendations from a broad array of databases and solutions to meaningfully influence GSK Oncology strategic trajectory.

Key Responsibilities

• Lead multiple workstreams and exert pronounced influence within cross-functional matrices.
• Harness the latest research and analytical methodologies to drive a competitive edge for GSK.
• Develop deep subject matter expertise across a broad array of tumor types, tracking trends, current and evolving competitive landscapes, and generating long-term strategic outlooks.
• Deliver well-integrated, actionable insights and ensure their strategic application to support global strategy, governance, and investment decisions.
• Drive commercial forecast generation to ensure seamless integration of market and customer insights into sound forecasts that contribute to stage gating and investment planning decisions.
• Manage vendor relationships to achieve a mutually rewarding partnership while ensuring excellence in insight generation execution.
• Leverage a wide range of tools and resources to identify opportunities, assess program potential, and provide guidance to optimize development plans.
• Ensure 100% adherence to market research compliance guidelines.

Basic Qualifications

• BA/BS Degree in Life Sciences, Applied Science, Analytics, Market Research, Healthcare Consulting or related.
• Significant experience within the pharmaceutical industry or in a consulting/agency environment supporting pharmaceutical clients.
• Extensive experience in commercial insights and analytics within Oncology,
• Experience working in qualitative and quantitative analysis related fields applying analytics and insights for business decisions (research, analytics, forecasting, etc.)
• Experience working on Business Development commercial assessments.
• Demonstrated ability to influence senior commercial leadership and confidently defend informed recommendations.
• Ability to leverage and synthesize a broad range of information sources to develop insight and generate clear, actionable recommendations that impact/drive decision-making at a business unit level.

Preferred Qualifications

• MBA, MS, or MA in business, marketing science, or science related.
• Experience in a matrix leadership position working in a cross-functional capacity.
• Preference will be attributed to applicants with both market research AND forecasting expertise.
• Research and analytics distillation, synthesis, and application to business issues and strong business acumen.
• Deep understanding of the pharmaceutical industry.
• Strong verbal and written communication/ presentation skills.
• Ability to work effectively across a matrix environment and influence without formal authority.
• Agility, flexibility, and comfort with ambiguity.

Closing Date for Applications – 11th March 2026 EOD

Please take a copy of the Job Description, as this will not be available post closure of the advert.  
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. 

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a  Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

The Onyx Research Data Tech organization represents a major investment by GSK R&D and Digital & Tech, designed to deliver a step-change in our ability to leverage data, knowledge, and prediction to find new medicines. We are a full-stack shop consisting of product and portfolio leadership, data engineering, infrastructure and DevOps, data / metadata / knowledge platforms, and AI/ML and analysis platforms, all geared toward:

• Building a next-generation data experience for GSK’s scientists, engineers, and decision-makers, increasing productivity and reducing time spent on “data mechanics”

• Providing best-in-class AI/ML and data analysis environments to accelerate our predictive capabilities and attract top-tier talent

• Aggressively engineering our data at scale to unlock the value of our combined data assets and predictions in real-time

Onyx Product Management is at the heart of our mission, ensuring that everything from our infrastructure, to platforms, to end-user facing data assets and environments is designed to maximize our impact on R&D. The Product Management team partners with R&D stakeholders and Onyx leadership to develop a strategic roadmap for all customer-facing aspects of Onyx, including data assets, ontology, Knowledge Graph / semantic search, data / computing / analysis platforms, and data-powered applications.

We are seeking an experienced Product Manager II who will be accountable for designing and delivering the road map for molecule design products to support GSK Research and Development. This role will be pivotal in ensuring a cohesive enterprise level strategy towards molecule design solutions and will ensure our scientists have access to best-in-in-class technology products to improve research productivity and ultimately deliver new medicines for our patients. You will:

• Contribute to Product Development & Adoption: Actively contribute to the full product lifecycle, from development to launch and adoption, focusing on specific features and components within novel molecule design solutions for the scientific community at GSK.

• Support GenAI Strategy: Support the strategic integration and enhancement of GenAI capabilities within molecule design tools, helping to define and implement next-generation AI-powered functionalities.

• Collaborative Delivery: Partner closely with Onyx tech teams, R&D scientists, and leaders to facilitate the delivery of impactful cloud-based products and solutions that leverage Generative AI and agentic capabilities.

In this role you will

• Product Strategy & Roadmap Contribution: Contribute to the definition and execution of specific features and components within the molecule design solutions roadmap, ensuring alignment with the overall product strategy.

• User Research & Feedback Analysis: Conduct user interviews, gather feedback, and analyze user data to inform the definition of product enhancements and identify opportunities for iterative improvements in molecule design tools.

• Product Feature Definition: Work closely with Senior Product Managers and engineering teams to translate user needs into clear, well-defined product requirements, user stories, and acceptance criteria for discrete features.

• Agile Development Engagement: Actively participate in agile ceremonies (e.g., sprint planning, backlog refinement, stand-ups) with engineering teams, ensuring product requirements are understood and supporting effective backlog management.

• GenAI Feature Implementation Support:

  • Contribute to the development and implementation of specific features within AI Agents, leveraging LLMs and Generative AI to automate well-defined parts of scientific research tasks.

  • Assist in the design and testing of human-agent interaction components, focusing on specific conversational flows or user interface elements to enhance usability.

  • Support the product lifecycle for individual models or agents by assisting with data gathering, testing of fine-tuned models, and developing documentation for APIs/agents.

  • Support the implementation of Model-In-The-Loop designs by gathering R&D user feedback and contributing to the

• Participate and contribute in highly technical product discussions with engineering leaders, translating ambiguous scientific objectives into precise requirements for fine-tuning foundational models, vector databases, and multi-agent system architectures.

• Cross-Functional Coordination: Coordinate with both tech and RD teams, including DevOps& Infrastructure, data engineering, computing platform engineering, data & knowledge platform engineering, program management teams and RD data leadership teams, to align product strategies, gather input, ensuring clear communication and smooth execution.

• Product Release Support: Assist with product launch activities for new features, including preparing documentation, training materials, and support resources to ensure successful adoption.

• Performance Monitoring & Optimization: Monitor key metrics for specific product features, gather user feedback on performance, and identify potential areas for improvement.

Why you?

Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals: 

• Bachelors degree in Bioinformatics, Computational Biology, cheminformatics, AI/ML, Computer Science, Software Engineering, or related discipline.

• Experience in product management with a proven track record of shipping 0-to-1 software products powered by AI/GenAI, LLMs, or autonomous agents in a commercial or large-scale enterprise setting.

• Demonstrated experience executing product strategy for modern applications, including hands-on experience with technologies core to AI systems such as vector databases, MLOps, retrieval-augmented generation, and model fine-tuning.

• Demonstrated technical fluency with cloud-native architectures (e.g., AWS, GCP, Azure), API design, and the infrastructure required to serve and scale LLM-based applications.

Preferred Qualifications & Skills:

If you have the following characteristics, it would be a plus:

• Master’s degree or PhD in Bioinformatics, Computational Biology, Computational Chemistry, Data Science, Computer Science/Software Engineering, or related discipline Engineering, Cloud Computing or related discipline.

• Experience contributing to products that involve AI agents, their tool utilization (APIs, function calling), or the development of conversational AI interfaces.

• Hands-on software engineering or data science experience in an AI/GenAI-focused team prior to transitioning into product management.

• Familiarity with the architecture of modern transformer-based models and an understanding of the strategic trade-offs when selecting between proprietary, open-source, or fine-tuned custom models.

• Experience contributing to products that manage or interpret complex, unstructured biomedical data.

• Familiarity with Model Context Protocols (MCP) for LLM-powered agents, including basic concepts of prompt engineering, context window management, and maintaining model coherence in multi-turn interactions.

• Foundational knowledge of bioinformatics, computational biology, or cheminformatics, and an interest in how agentic AI can impact drug discovery.

• Hands-on experience with product management tools such as Confluence, Jira, Miro, Monday, Notion, etc.

• Previous experience in the life science industry or biopharma R&D is a plus.

Closing Date for Applications: Wednesday 25th March 2026 (COB)

Please note: As we approach the holiday season, our recruitment team and hiring managers will have limited availability between now and early January. We encourage you to apply and will review all applications, however response times may be longer than usual, and interviews may be scheduled after the New Year. We appreciate your understanding and look forward to connecting soon!

Please take a copy of the Job Description, as this will not be available post closure of the advert. 
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application, you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process.  If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.

#LI-GSK

#GSKOnyx

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a  Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

GSK is seeking a Clinical Development Medical Director - Hepatology to act as a translational leader within the Early Pipeline Unit (EPU) of the Respiratory, Immunology and Inflammation Research Unit (RIIRU). The successful individual will provide medical and scientific expertise to pre-clinical, clinical and translational studies. They will lead programs or work within project teams to conceptualize, design, plan and execute projects including first-time-in-human trials for new assets, experimental medicine studies and translational data generation. They will work cross-functionally to develop and execute clinical development plan(s) up to, and including, Proof of mechanism/Proof of concept studies. This is an exciting opportunity to bring new therapies into the clinic with a particular focus on treatments for steatotic liver disease (including MASH and ALD) and chronic Hepatitis B.

Key Accountabilities / Responsibilities:

• Drive development of clinical plans and study designs and ensure alignment with translational plans and project strategies to ensure quality execution of the clinical development plan. Will develop sections of core regulatory documents.
• Generate the data and evidence required to determine a target or medicines’ potential efficacy, safety profile, key areas of product differentiation and route to becoming a medicine with value to patients in the shortest possible timeframe
• Deliver clinical development and study timelines and endpoints, including pharmacology, mechanism and clinical efficacy endpoints, enabling key decision points and Go/No Go criteria for the CDP.
• Seek and maintain relationships with program counterparts in Biology, Translational, Commercial, Research, Regulatory, Clinical Operations, Access, Medical Affairs and Statistics.
• Contribute to the implementation and embedding of strategic initiatives and various organizational initiatives in Clinical Development

Clinical Development Strategy; Study & Program Design:

• Designs clinical development plans and study protocols across all phases of development, reflecting internal and external stakeholder input (e.g. patients, evidence generation, regulators, payors, pharmacovigilance)
• Develops clinical study protocols, amendments, investigator brochures and clinical study reports.
• Contributes to the study team discussions on indication planning, incorporates input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc) to contribute to vital deliverables including early Medicine Profile, Target Validation, Translational Plans, Candidate Selection.
• Provides effective support and oversight of R&D evidence generation activities to assure patient safety and study delivery.
• Inputs to regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.
• Provides medical monitoring and oversight of the safety of study participants on behalf of the Sponsor during the study, together with Pharmacovigilance Physician. Accountability for Medical
• Governance across the project to ensure scientific integrity and overall safety of the study subjects across the study.

Clinical Leadership:

• Actively leads the end-to-end clinical development strategy for an EPU program and may contribute to later stages. Accountable for leading the CMT on an EPU program. Serves as a clinical point of contact both internally and externally for an indication of an asset indication (i.e. Pre-POC and single indication) or for a clinical study. Represents the clinical matrix team at EDT or clinical study at CMT.
• Collaborate with cross-functional teams, including biology, translational, regulatory affairs, medical affairs, and commercial teams, to ensure cohesive and comprehensive translational and clinical development plans. Act as Clinical Lead at study level.
• Serves as the primary clinical interface with the relevant internal RIIRU/GSK review board (ie Technical Review or governance) and/or Protocol Review Board.
• Clinical evaluation of business development opportunities.
• Stays abreast of advancements in hepatology research, clinical trial methodologies, competitive environment and regulatory space to maintain GSK’s competitive edge. Identifies and highlights transformational opportunity where projects can offer highly significant benefit to patients in ways not possible with existing approaches.
• Gathers and supports the integration of inputs from across disciplines (scientific, clinical commercial, regulatory) to contribute to clinical components of the Medicine Profile. Consistently contributes to solving study and overall clinical development plan problems.
• Contributes to the implementation and embedding of strategic initiatives and various organizational initiatives in the EPU.
• Demonstrates ability to influence others at project, departmental and inter-departmental levels, as appropriate

Influencing and inspiring others, managing conflict:

• Able to consistently inspire others by setting a positive example, communicating a compelling vision, and creating an environment where team members feel valued and motivated.
• Demonstrated experience in managing conflicts effectively and independently, negotiating mutually acceptable solutions.
• Consistently achieves desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support.

Enterprise mindset and navigating ambiguity:

• Demonstrated flexibility and adaptability in changing environments, able to analyze incomplete information, identify potential risks and implications, and make informed decisions.
• Demonstrated enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.
• Embraces challenge as an opportunity for creativity and uses new learning and digital tools to create innovation in other areas
• Proactively generates ideas for innovative improvement and takes advantage of opportunities that arise; promotes environment for others to generate ideas for improvement

Why You?

Basic Qualifications:

We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

• Medical Degree required; general internal medicine or alternative experience in a relevant disease area preferred
• Completion of clinical residency and appropriate specialty training, ideally including hepatology experience
• Experience in preclinical or clinical research and development (may include postgrad experience)
• Knowledge and experience in the execution of translational studies including both generation and analysis of human translational data and/or conduct of preclinical biological experiments in relevant model systems
• Robust knowledge of hepatology specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolution.
• Knowledge of regulatory requirements, Good Clinical Practice (GCP), and ethical guidelines for clinical research.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• PhD or other higher research degree
• Board certified/eligible in gastroenterology with focus in hepatology
• Experience working with global regulatory agencies and managing global clinical trials in hepatology.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a  Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D

GSK is seeking a Medical Director, Clinical Development, APU Respiratory to provide clinical and scientific insights to potential new, established and emerging assets in clinical development with a strong focus on respiratory disease You will work within project teams to plan, execute, and deliver clinical development activities and support medical governance up to and including registrational studies. This role is pivotal in driving GSK’s mission to deliver transformative medicines to patients, ensuring clinical excellence, regulatory compliance, and operational efficiency.

About RIIRU:

The Respiratory, Immunology and Inflammation Research Unit (RIIRU) was formed in 2024 to identify and advance novel molecular targets with genetic associations to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two-fold. The remit of RIIRU is to identify novel targets based on human genetics, develop assets for clinical studies, and perform trials through to submission for approvals. This goal is enabled through strategic external (e.g., Flagship Pioneering, Vesalius, Muna Therapeutics and others) and GSK-internal partnerships (Research Technologies).  

PLEASE NOTE: This career opportunity requires an on-site office presence (minimum of two days a week) at one of GSK’s US (PA or MA) or UK (Stevenage or London HQ) sites.

Key Responsibilities:

This role will provide YOU opportunity to lead key activities to progress your career, these responsibilities include some of the following:

• Contribute to project team discussions on indication planning and incorporate input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc) to support vital deliverables including the Target Medicine Profile (TMP), clinical development plan (CDP), study protocols, and integrated evidence strategy (IES) and planning. 
• Provide effective support to the development and execution of the IES, including oversight of R&D evidence generation activities to ensure patient safety and study delivery.
• Design and execute clinical development plans across advanced stages of development, reflecting internal and external stakeholder input (ie patients, evidence generation, regulators, payors, pharmacovigilance, etc.).
• Contribute to ambitious clinical development timelines by overseeing development of clinical study protocols, amendments, investigator brochures, clinical study reports etc.
• Input to, and may lead, regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.
• Provide medical monitoring and oversight of the safety of study participants.
• Act as clinical lead for a clinical study, taking a key role on the Study Leadership Team (SLT) and serve as clinical point of contact for a clinical study on the Clinical Matrix Team (CMT), across the internal matrix and a broad range of external experts (e.g., regulators, payors, CROs, consultants, investigators).
• Make significant contributions to global regulatory submissions/files (e.g., IND, NDA, BLA, MAA), including briefing documents, presentations, and responses to regulatory questions.
• Evaluate specific business development activities, including due diligence and contributes to the implementation and embedding of strategic/organizational initiatives in Clinical Development, adopting innovative methodologies and processes including digital tools and technology.
• Stay abreast of advancements in therapeutic area research, clinical trial methodologies, competitive environment, and regulatory space to maintain GSK’s competitive edge.

In addition to the above, YOU will:

• Demonstrate flexibility and adaptability in changing environments and ability to analyze incomplete information, identify potential risks and implications, and make informed decisions.
• Demonstrate enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.
• Embrace challenge as an opportunity, proactively generating ideas for innovative improvement and promoting an environment for others to be creative.
• Manage conflicts effectively and independently, negotiating mutually acceptable solutions.
• Analyze, interpret and critically evaluate data, information and digital content  to interpret complex information, anticipate obstacles and identify potential solutions.
• Consistently achieve desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support.

Basic Qualifications

We are looking for professionals with these required skills to achieve our goals:

• Medical Degree
• Completion of formal postgraduate clinical training (e.g., Internal Medicine, Primary Care / Family Medicine), leading to board eligibility or certification.
• Experience in clinical research and drug development, including experience relevant to respiratory diseases.

Preferred Qualifications

If you have the following characteristics, it would be a plus:

• Medical degree with formal specialty training and board qualification/registration in Pulmonary Medicine, Pulmonary & Critical Care, or Respiratory Medicine.
• Experience working in the global pharmaceutical or biotechnology industry within respiratory diseases.
• Experience leading global clinical trials and contributing to NDA, BLA, or MAA submissions.
• Experience in late‑stage respiratory drug development, including design, initiation, execution, and closure of Phase 2 and Phase 3 clinical trials.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.

Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job Purpose

The Associate Director, Wearable Sensor Technology is responsible for the design, evaluation, and integration of advanced digital sensor technologies into GSK’s clinical programs. This role blends technical depth and strategic insight to advance our next generation of wearable solutions across health monitoring, human performance, physiological measurement, and digital biomarker innovation.

You will collaborate closely with data scientists, hardware engineers, software developers, clinicians, and product stakeholders to deliver high‑accuracy, validated sensor technologies that are robust, scalable, and regulatory‑ready.

This role requires 2-3 days on-site per week average at one of these preferred sites: USA - Collegeville, PA at our Upper Providence Site. UK - GSK Head Quarters. Other arrangements considered on a case by case basis.

Key Responsibilities:

Accountable to Head of Digital Measures and COA Methodology, the responsibilities listed below outline the scope of the position. The application of these tasks may vary, based upon evolving business needs.

Sensor Technology

• Lead the selection, design, and integration of wearable and ambient sensors and devices (e.g., PPG, ECG, accelerometry, IMUs, EMG, EEG, bioimpedance, temperature, sweat chemistry, environmental sensors).

• Develop and optimize sensor configurations, placement strategies, sampling protocols, and signal quality architectures.

• Oversee prototyping, bench testing, and hardware validation activities.

Signal Processing & Algorithm Development

• Provide input to signal processing pipelines for noise reduction, artifact removal, feature extraction, and real‑time analytics.

• Partner with data science teams to develop algorithms for physiological measurement, digital biomarkers, or activity classification.

• Evaluate sensor performance using statistical, biomechanical, and physiological validation frameworks.

Wearable System Architecture

• Critically assess and contribute to system‑level design considerations, including sensor signal conditioning and sampling, power management strategies, connectivity, on‑device computing, and cloud integration architectures.

• Assess manufacturability, longevity and ergonomics.

Clinical, Regulatory, and Validation Support

• Design validation studies following FDA, EMA, or MDR-aligned frameworks, including GCP/GCLP where applicable.

• Collaborate with clinical teams to ensure that systems have adequate usability, reliability, repeatability, and suitability for the intended endpoints.

• Drive documentation for verification, validation, compliance, and quality systems.

Cross‑Functional Collaboration

• Partner with UX and product teams to create user‑centric wearable experiences.

• Communicate technical findings clearly to non‑technical audiences and executive stakeholders.

• Evaluate vendor offerings, academic partnerships, and emerging wearable technologies.

Why You?
 

Basic Qualifications:

We are seeking professionals with the following required skills to achieve our goals:

• Master’s degree in a relevant scientific discipline (e.g., biomedical engineering, electronic engineering, physics, etc).

• 5+ years of progressive experience in pharmaceutical R&D, biotech, digital health, or a relevant contract research organisation (CRO) with a focus on digital health technologies for clinical research.

• Experience with a broad range of digital sensing technologies (e.g. Accelerometers, gyroscopes, inertial MEMS, PPG, ExG, thermal, acoustic, pressure, chemical and biochemical sensors), with a strong understanding of associated signal conditioning requirements and underlying signal characteristics.

• Experience in the development, validation, and implementation of digital health technologies for clinical research and/or real-world evidence generation.

• Experience with signal processing, advanced analytics, machine learning, and artificial intelligence applied to digital health data.

• Regulatory experience related to digital health technologies and guidances.

• Published peer-reviewed articles and/or presented at major scientific conferences in the field of digital measures, COA, or related areas.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• PhD in a relevant scientific discipline (e.g., biomedical engineering, electronic engineering, physics, etc).

• Global experience and a nuanced understanding of international regulatory landscapes for digital health.

• Experience with COA methodology, including PRO, ClinRO, and PerfO instrument development, validation, analysis, and interpretation of results.

• Experience of navigating the drug development process and regulatory pathways (e.g., IND/NDA/BLA submissions where COA/digital measures are key endpoints).

• Experience preparing regulatory submissions related to COA and digital measures (e.g., FDA Q-submissions, briefing books) and participating in regulatory agency meetings (including advisory committee presentations).

• An understanding of measurement theory, psychometrics and statistical analysis applied to clinical outcomes.

• Scientific Acumen: Deep understanding of biosensing mechanisms, signal characteristics, and measurement science to evaluate, validate, and integrate diverse sensor technologies into clinical programs.

• Communication & Influence: Strong written and verbal communication skills, with the ability to translate complex scientific and technical information for diverse audiences (scientific, clinical, regulatory, leadership).

• Collaboration & Cross-functional Influence: An ability to build strong relationships, collaborate effectively across functions, and influence without direct authority.

• Problem-Solving & Innovation: Analytical and critical thinking skills, with an ability to solve complex problems and drive innovative solutions.

• Agile Mindset: Capable of fostering an iterative and learning-oriented team environment.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.

Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

GSK is seeking a strategic and innovative leader to drive the digital transformation of Finance and Procurement operations. This role will serve as a key partner to senior stakeholders across Finance, Procurement, and Technology, leading the development and execution of a unified digital strategy that leverages AI, automation, and ERP integration to deliver operational excellence and cost efficiency.

Key Responsibilities:

Strategic Leadership & Partnership

• Align digital strategies with business objectives across Finance and Procurement.
• Collaborate with the Finance and Procurement stakeholders to shape and deliver transformation initiatives.
• Translate business needs into actionable technology strategies.

Finance Transformation

• Lead reengineering of core finance processes including Source to Pay (S2P), Record to Analyse (Close and Control), Tax Operations, and General Finance Operations.
• Implement scalable, cost-effective solutions using agent-based ecosystems to reduce service costs by up to 50%.
• Define clear roadmaps and execution plans for digital initiatives.

Procurement Technology Leadership

• Oversee all Procurement Tech products and services, including SAP Ariba (Spend Analytics, Sourcing, Contract Management, Guided Buying), Jaggaer, SAP Concur T&E, SAP Fieldglass, and ECC Procurement.
• Lead patching, upgrades, and ensure system currency without disrupting operations.
• Manage vendor relationships and ensure service delivery meets contractual obligations.

Technology Innovation

• Architect next-generation solutions that support dynamic business needs.
• Design and implement self-learning agents for cross-process optimization.
• Integrate AI solutions with existing ERP and financial platforms.

Operational Excellence

• Provide L3 support and manage major incidents, including SWAT calls.
• Run AARs and ensure implementation of outcomes.
• Lead cross-product agile teams and manage backlogs for multiproduct assets.

Performance & Continuous Improvement

• Define and monitor KPIs to assess digital solution effectiveness.
• Establish feedback loops and reinforcement learning mechanisms.
• Foster a culture of innovation and continuous improvement.

Required Qualifications:

• University degree or equivalent.
• Director level of experience in finance and procurement transformations.
• Proven delivery across at least three core finance processes.
• Deep expertise in AI, automation, and ERP integration.
• Extensive experience with SAP Ariba, Concur, Fieldglass, and Cloud Integration Gateway.
• Strong leadership and stakeholder engagement skills in a matrixed global environment.
• Experience in agile and product management methodologies.
• Vendor management experience (MSPs).

Preferred Qualifications:

• SAP certification in Procurement Tech product areas.
• Strong project and program planning skills.
• Ability to lead cross-cultural, virtual teams.
• Excellent problem-solving and communication skills.

#GSK-LI

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a  Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Position Summary

General Medicines is a £10 billion business (30% of GSK sales) and is expected to maintain stable turnover over the next three years. The International Markets business grew 4% in 2025 to reach £8.2 billion, making it the second-largest region after the US, and it is on track to deliver high single-digit profitable growth in General Medicines in 2026. In this context, GSK’s Primary & Small Molecules (PSM) network manufactures most of General Medicines’ volumes, supporting circa 60% of revenues and more than 30% of the growth.

The VP, Local to Local Operations role is instrumental in delivering this commercial ambition, with overall accountability for executing company strategy and delivering P&L across 8 of the 14 manufacturing sites in the Primary & Small Molecules network, operating across North Africa, the Middle East and Asia (Algeria, Egypt, Japan, Saudi Arabia, and Pakistan). The role is accountable for ensuring performance excellence across the GSK portfolio in the area, as well as for the strategic direction established in collaboration with the Local Operating Companies (LOCs).

Key Responsibilities in Detail

Drive and manage the business

•  Together with the SVP, Primary & Small Molecules, and the Global Supply Chain (GSC) strategy group, define the Local to Local manufacturing operations strategy, ensuring the highest level of delivery, commercial alignment, and returns.

•  Together with the Local to Local Leadership Team, deliver the objectives of the business in partnership with Commercial, driving one P&L mindset and business impact.

•  Together with the Site Directors, partner with Commercial to maximise gross margin through appropriate cost, profit, and revenue goals.

•  Drive operational performance and ensure continuous supply of medicines in the markets, in line with GSK KPIs and meeting customer needs.

•  Manage GSK resources effectively to deliver the longer-term strategy, portfolio evolution, and performance ambition.

•  Provide leadership to Site Directors and manufacturing sites to ensure a continuous supply of medicines. Ensure flawless operational delivery across sites, at the right cost and with the right quality.

•  Ensure the Site Directors lead with an enterprise mindset, building market agility and ensuring commercial alignment.

•  Effectively manage GSK Enterprise Risks and Compliance and be relentlessly focused on Safety.

•  Be accountable for ensuring GSK operates in line with all locally and globally applicable laws, policies, SOPs, and legislation, including EHS, Quality, and financial reporting.

•  Ensure regulatory alignment.

People

•  With the Local to Local Leadership Team, provide leadership and engage all employees in delivering the objectives to expectations.

•  Inspire, engage, and align employees to understand and deliver the strategy.

•  Lead, evaluate, and develop senior leaders and teams, and have the ambition to foster Enterprise leaders.

•  Foster a high-performing team environment, in compliance with all relevant internal and external regulations and laws.

•  Attract, develop, and retain talent at all levels to ensure quality succession plans for priority roles in the organisation.

Performance culture

•  Be a role model and set the right tone from the top in embedding the GSK culture.

•  Drive a culture of continuous improvement and learning and personally drive LEAN and Digital as a way of working.

•  Create an environment that recognises and rewards high performance and actively manages underperformance.

•  Create an atmosphere of trust, fostering open and honest conversations across the organisation, and be an active communicator.

Corporate reputation & trust

•  Initiate and grow appropriate relationships with external bodies, health communities, and industry associations.

•  Build strong cross-functional relationships to maximise synergies and make sure that GSK has unified, coherent, and trusted representation externally.

•  Embed a preventive EHS mindset within Local to Local Operations.

•  Build a strong quality culture within Local to Local Operations.

•  Ensure site compliance of all operations with Quality and Regulatory requirements.

•  Ensure all respective sites comply with GSK and local health, safety, and environment requirements.

•  Maintain good relationships and a good employee relations environment.

Candidate Profile - Qualifications & Expertise

Basic Qualification

We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

•  Proven leadership experience running an independent site in the pharmaceutical sector.

•  Experience in pharmaceutical manufacturing operations and with quality, compliance, and risk requirements in a pharmaceutical environment.

•  Experience in building a culture of continuous improvement and embedding strong safety and quality systems and behaviours.

•  Experience in leading leaders across cultures and building high‑performing, inclusive teams.

•  Fluent in English and able to travel internationally.

Preferred Criteria

•  Proven leadership experience running multiple manufacturing sites or a manufacturing network in the pharmaceutical sector.

•  Additional experience in regional or global Quality, Supply Chain, or Engineering roles, or leading sites in different business contexts.

•  Experience working across developed and emerging markets or with multi-country operations.

•  Ability to anticipate future opportunities and challenges and turn them into clear operational goals.

•  Engaging, empowering, inclusive, and decisive leadership style with well-developed relation building skills to build trust and credibility and establish networks across markets, Commercial and other functions at a regional and global level.

•  Enterprise thinking.

•  Cultural sensitivity and ability to work effectively across cultures.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a  Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Business Introduction
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D


Position Summary

The Respiratory, Immunology and Inflammation Translational Unit (RIITU), within RIIRU therapy area is accountable for end-to-end disease area translational science to inform therapy area and program level biomarker strategies (from preclinical to launch) to increase the probability of success from preclinical to clinical transitions and enable earlier and higher confidence asset related decisions. This includes generation of foundational data as well as disease biomarker development and validation that allow timely deployment of tools/biomarkers to support Proof of Mechanism (PoM), signs of clinical efficacy, Proof of Concept (PoC), and pairing Mechanisms of Action (MoAs) with patient subtypes to predict responder populations. We are looking for a dynamic individual to excel in the following responsibilities.

Key Responsibilities:

Disease Biomarker Strategy Development and Delivery:

o Partner with the Clinical Teams, Research Technologies and the Development organization with focus on Respiratory portfolio to identify, establish biomarkers for decision making throughout clinical development phases and aligned with the overall research and development goals. This will include the identification, prioritization and validation of disease relevant biomarkers, mechanistic/surrogate biomarkers, patient stratification, and differentiated response prediction, their deployment into clinical studies and interpretation of data/results.

Translational Leadership:

o Provide strategic leadership contributing to deep understanding of Disease areas enabling the development and execution of translational research disease strategies to support the discovery and development of novel differentiated therapeutics including evaluation and diligence of business development opportunities.

Translational innovation:

o Evaluate novel techniques and technologies (i.e. spatial transcriptomics) to inform translational initiatives, biomarker development and validation working in collaboration with platform teams and within a multi-functional matrix environment.

o Identify and guide validation of human assays (cells, tissues and organs) to enhance human translation and predictive value through the application of resources such as the Human Cell Atlas, disease tissue multi-omics data and genetic resources (external or proprietary).

Cross-functional Collaboration:

o Collaborate closely with cross-functional teams including the Translational, Disease Teams, Human Genetics & Genomics, biology groups, biomarker platforms, Medicine Development Teams, HBSM, data-sciences, regulatory affairs, business development and commercial to ensure seamless integration of translational research and biomarker strategies across the drug development lifecycle.

External Partnerships:

 o Establish and maintain strategic collaborations with academic institutions, contract research organizations (CROs), and other external partners to access cutting-edge technologies, tools, reagents, biosamples, biomarker expertise, and research capabilities. o Foster a network of external experts and key opinion leaders to stay at the forefront of translational science and biomarker advancements across the industry.

 o Contribute to evaluation and diligence of business development opportunities.

Matrix Leadership:

o Provide mentorship, guidance, and professional development opportunities to ensure a high-performing and motivated team.

o Manage disease and project level resources, budgets, and timelines to ensure the successful execution of projects and achievement of milestones and RITU objectives.

o Represent RITU at portfolio governance reviews providing critical input to pipeline and investment decision making.

Why You?

Basic Qualification
We are seeking professionals with the following required skills and qualifications to help us achieve our goals

• Ph.D. in a relevant scientific discipline (e.g., Cell/Molecular Biology, Genetics, Pharmacology, Physical Chemistry or related field)
• Extensive experience in translational science and biomarker development ideally within the pharmaceutical or biotechnology industry.
• Recognised translational/biomarker expert in scientific community through publications and contributions to the field.
• Experience of translation and biomarkers implementation in Respiratory indications
• Experience of working in a clinical trial setting, working as part of a clinical study and experience of authoring and oversight of clinical and regulatory documents

Preferred Qualification
If you have the following characteristics, it would be a plus

• Knowledge of regulatory requirements, industry standards, best practices and compliance considerations in Translational Research and biomarker development and validation.
• Broad knowledge in technologies and methods used in translational research.
• Proven track record of program decision making through implementing biomarker strategies and delivering translational science insights in support of drug progression through clinical transition milestones.
• Experience leading/managing external collaborations and evaluation of business development opportunities.
• Strong management skills, with the ability to prioritize and manage multiple objectives to meet timelines while maintaining attention to detail and high-performance standards.
• Excellent inclusive matrix leadership skills, with the ability to create psychological safety, inspire and motivate a team towards achieving common goals.

Working Model
This role is based in the United Kingdom or the United States and follows a hybrid working model. You will be expected to work on site regularly to collaborate with your team and partners.

How to apply
If this role inspires you, please apply with your CV and a short cover note describing a recent translational achievement. Tell us what you did, why it mattered, and the impact it had. We welcome people from all backgrounds and value inclusion in how we hire and lead. We look forward to hearing from you.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a  Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/